Cytogem 1 gm/vial (IV Infusion)
1 gm vial: ৳ 4,700.00
Medicine Details
Category | Details |
---|---|
Generic | Gemcitabine |
Company | Drug international ltd |
Also available as |
Indications
- Non-Small Cell Lung Cancer treatment
- Pancreatic Cancer treatment
- Bladder Cancer treatment
- Breast Cancer treatment
- Ovarian Cancer treatment
Pharmacology
- Metabolism by nucleoside kinases
- Cytotoxic action on DNA synthesis
- Inhibition of ribonucleotide reductase
- Competes for incorporation into DNA
- Induces apoptosis
Dosage & Administration
- Recommended dosage for different cancers
- Intravenous infusion dosing schedules
- Dosage reduction based on toxicity
- Use in combination therapy
Interactions
- No confirmed drug interactions reported
- No specific drug interaction studies conducted
Contraindications
- Known hypersensitivity to Gemcitabine
Side Effects
- Haematological toxicity
- Hepatic toxicity
- Gastrointestinal effects
- Genito-urinary toxicity
- Pulmonary toxicity
- Allergic toxicity
- Neurotoxicity
- Alopecia
Pregnancy & Lactation
- Pregnancy Category D
- Use during pregnancy
- Unknown excretion in breast milk
Precautions & Warnings
- Caution in patients with specific risks
Use in Special Populations
- Elderly patients tolerance
- Renal and Hepatic Impairment caution
- Limited data on use in children
Overdose Effects
- No known antidote
- Principal toxicities observed
- Monitoring and supportive therapy
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Store in original carton at 20°C to 25°C
- Avoid refrigeration to prevent crystallisation
- Keep out of the reach of children
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