Cytogem 1 gm/vial (IV Infusion)

1 gm vial: ৳ 4,700.00

Medicine Details

Category Details
Generic Gemcitabine
Company Drug international ltd
Also available as

Indications

  • Non-Small Cell Lung Cancer treatment
  • Pancreatic Cancer treatment
  • Bladder Cancer treatment
  • Breast Cancer treatment
  • Ovarian Cancer treatment

Pharmacology

  • Metabolism by nucleoside kinases
  • Cytotoxic action on DNA synthesis
  • Inhibition of ribonucleotide reductase
  • Competes for incorporation into DNA
  • Induces apoptosis

Dosage & Administration

  • Recommended dosage for different cancers
  • Intravenous infusion dosing schedules
  • Dosage reduction based on toxicity
  • Use in combination therapy

Interactions

  • No confirmed drug interactions reported
  • No specific drug interaction studies conducted

Contraindications

  • Known hypersensitivity to Gemcitabine

Side Effects

  • Haematological toxicity
  • Hepatic toxicity
  • Gastrointestinal effects
  • Genito-urinary toxicity
  • Pulmonary toxicity
  • Allergic toxicity
  • Neurotoxicity
  • Alopecia

Pregnancy & Lactation

  • Pregnancy Category D
  • Use during pregnancy
  • Unknown excretion in breast milk

Precautions & Warnings

  • Caution in patients with specific risks

Use in Special Populations

  • Elderly patients tolerance
  • Renal and Hepatic Impairment caution
  • Limited data on use in children

Overdose Effects

  • No known antidote
  • Principal toxicities observed
  • Monitoring and supportive therapy

Therapeutic Class

  • Cytotoxic Chemotherapy

Storage Conditions

  • Store in original carton at 20°C to 25°C
  • Avoid refrigeration to prevent crystallisation
  • Keep out of the reach of children

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