Gemcitabine PhaRes 1 gm/vial (IV Infusion)

1 gm vial: ৳ 7,025.00

Medicine Details

Category Details
Generic Gemcitabine
Company Thymoorgan pharmazie gmbh germany
Also available as
Gemcitabine phares 200 mg injection

Indications

  • Non-Small Cell Lung Cancer treatment
  • Pancreatic Cancer treatment
  • Bladder Cancer treatment
  • Breast Cancer treatment
  • Ovarian Cancer treatment

Pharmacology

  • Metabolized by nucleoside kinases
  • Inhibition of DNA synthesis
  • Inhibition of ribonucleotide reductase
  • Competes with dCTP for incorporation into DNA
  • Induces programmed cellular death process

Dosage & Administration

  • Recommended doses for Non-Small Cell Lung Cancer
  • Recommended doses for Pancreatic Cancer
  • Recommended doses for Bladder Cancer
  • Recommended doses for Breast Cancer
  • Recommended doses for Ovarian Cancer

Interaction

  • No confirmed interactions reported
  • No specific drug interaction studies conducted

Contraindications

  • Contraindicated in patients with known hypersensitivity to Gemcitabine

Side Effects

  • Haematological Toxicity
  • Hepatic Toxicity
  • Gastrointestinal effects
  • Genito-Urinary Toxicity
  • Pulmonary Toxicity
  • Allergic Toxicity
  • Neurotoxicity
  • Alopecia

Pregnancy & Lactation

  • Pregnancy Category D
  • Use during pregnancy
  • Unknown excretion in human breast milk

Precautions & Warnings

  • Caution for Schedule-dependent Toxicity
  • Caution for Myelosuppression
  • Caution for Pulmonary Toxicity and Respiratory Failure
  • Caution for Hemolytic Uremic Syndrome
  • Caution for Embryofetal Toxicity
  • Caution for Radiation Therapy Toxicity
  • Caution for Impairment of Fertility

Use in Special Populations

  • Elderly Patients
  • Renal and Hepatic Impairment
  • Children

Overdose Effects

  • No known antidote
  • Principal toxicities include myelosuppression and paresthesias

Therapeutic Class

  • Cytotoxic Chemotherapy

Storage Conditions

  • Store at 20°C to 25°C away from light
  • Do not refrigerate to avoid crystallization
  • Keep out of reach of children

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