Cortiflo 6 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Nuvista pharma ltd |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Systemic lupus erythematosus
- Dermatomyositis
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anaemia
- Idiopathic thrombocytopenic purpura
- Acute and lymphatic leukaemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
- Anti-inflammatory action
- Inhibition of Phospholipase A2 enzyme
- Prostaglandin synthesis
- Immunosuppressive action
- Decreased release of certain immune system chemicals
Dosage & Administration
- Adults dosage range: Up to 120 mg/day initial dose
- Maintenance doses for adults: 3-18 mg/day
- Children dosage range: 0.25-1.5 mg/kg/day
- Deflazacort withdrawal guidance
Interaction
- Metabolized in the liver
- Maintenance dose adjustment with liver enzyme inducers
- Possible reduction of maintenance dose with liver enzyme inhibitors
Contraindications
- Hypersensitivity to ingredients
- Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal effects
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Striae
- Telangiectasia
- Acne
- Myocardial rupture risk
- Thromboembolism risk
Pregnancy & Lactation
- Placenta crossing potential
- Risk of intrauterine growth retardation with prolonged use
- Excretion in breast milk
- Recommendation for prescription evaluation in pregnancy
- Infant systemic effects with high maternal doses
Precautions & Warnings
- Special caution for cardiac disease or congestive heart failure
- Salt and water retention risk
- Increased potassium excretion
- Caution with gastritis or oesophagitis
- Thromboembolic disorders
- Potential for perforation
- Diabetes mellitus and family history
- Osteoporosis risk
- Myasthenia gravis
- Renal insufficiency
- Emotional instability or psychotic tendency
- Epilepsy caution
- Previous corticosteroid-induced myopathy concern
- Liver failure
- Hypothyroidism and cirrhosis effect
- Ocular herpes simplex caution
Use in Special Populations
- Hepatic impairment monitoring and dose adjustment
- Renal impairment precautions
- Elderly patient considerations
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Cool and dry storage
- Protected from light & moisture
- Keep out of the reach of children