Gerdo 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.02 (7 x 7: ৳ 343.98)
Strip Price: ৳ 49.14

Medicine Details

Category Details
Generic Esomeprazole
Company Nuvista pharma ltd

Title

  • Gerdo 20 mg Capsule

Categories

  • Proton Pump Inhibitor
  • Gastroesophageal Reflux Disease (GERD) Relief
  • Erosive Esophagitis Healing
  • Duodenal Ulcer Disease
  • Gastric Ulcer Healing
  • Symptomatic GERD Relief
  • Acid-Related Dyspepsia Relief

Description

  • Gerdo 20 mg Capsule is a proton pump inhibitor (PPI) indicated for relieving chronic heartburn symptoms and other symptoms associated with GERD, healing of erosive esophagitis, maintaining healing of erosive esophagitis, eradicating Helicobacter pylori infection, treating Zollinger-Ellison Syndrome, dyspepsia, duodenal and gastric ulcer.
  • It works by suppressing gastric acid secretion through specific inhibition of the H+/K+-ATPase, providing better acid control than racemic proton pump inhibitors, and is available in oral and IV dosage forms.

Dimensions

  • Single Capsule: 20 mg or 40 mg
  • Dosage Forms: Oral Capsules, Oral Suspension, IV Injection/Infusion

Color options

  • White

Functions

  • Relieves Chronic Heartburn Symptoms
  • Heals Erosive Esophagitis
  • Maintains Healing of Erosive Esophagitis
  • Eradicates Helicobacter pylori Infection
  • Treats Zollinger-Ellison Syndrome
  • Relieves Acid-Related Dyspepsia
  • Heals Duodenal & Gastric Ulcers
  • Reduces Risk of Rebleeding of Gastric or Duodenal Ulcers following Therapeutic Endoscopy
  • Suppresses Gastric Acid Secretion
  • Provides Better Acid Control
  • Inhibits Gastric Acid Secretion
  • Interferes with the Absorption of Drugs Dependent on Gastric pH

Materials

  • Esomeprazole Magnesium
  • Enteric-Coated Pellet Formulation

Technical specifications

  • Absorption: Peak plasma levels occur at approximately 1.5 hours after oral administration
  • Distribution: 97% bound to plasma proteins
  • Metabolism: Extensively metabolized in the liver by the cytochrome P450 enzyme system
  • Excretion: Less than 1% of the parent drug is excreted in the urine
  • Combination therapy with antimicrobials: Esomeprazole magnesium 40 mg once daily given in combination with clarithromycin and amoxicillin for 7 days
  • Iv injection or infusion: Adult Patients: 20 mg or 40 mg once daily, IV Injection >3 Minutes, IV Infusion 10-30 minutes; Pediatric Patients: Dose adjusted by body weight

Design elements

  • Clear and Colorless to Very Slightly Yellow Reconstituted IV Injection Solution
  • Esomeprazole Capsules should be Swallowed Whole and Taken One Hour before a Meal

Usability features

  • Tablet or Capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension should be taken with water and stirred well before consumption
  • IV Injection solution must be prepared using 0.9% Sodium Chloride and administered intravenously over at least 3 minutes

Interaction

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, and 3A4
  • No clinically relevant interactions with drugs metabolized by these CYP enzymes expected
  • May interfere with CYP2C19 and gastric pH-dependent drug absorption
  • Co-administration of certain drugs may result in altered plasma levels of esomeprazole and 14-hydroxyclarithromycin

Contraindications

  • Known Hypersensitivity to Esomeprazole Formulations

Side effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal Pain
  • Constipation
  • Dry Mouth

Pregnancy and lactation

  • No Adequate and Well-Controlled Studies in Pregnant Women
  • No Teratogenic Effects in Animal Studies
  • Excretion in Milk Not Studied
  • Breastfeeding should be Discontinued if Essential to Use Esomeprazole

Precautions and warnings

  • Symptomatic Response to Therapy does not Exclude Gastric Malignancy
  • Capsules should be taken at least one hour before meals
  • Antacids may be used while taking Gerdo

Special populations use

  • Safety and Effectiveness not Established in Paediatric Patients
  • No Overall Differences in Safety and Efficacy between Elderly and Younger Individuals
  • No Dosage Adjustment Recommended for Patients with Mild to Moderate Hepatic Insufficiency
  • No Expected Alteration in Pharmacokinetics in Renal Impairment

Overdose effects

  • A single oral dose of Gerdo at 510 mg/kg has been lethal to rats
  • Major Signs of Acute Toxicity Include Reduced Motor Activity, Changes in Respiratory Frequency, Tremor, Ataxia, and Intermittent Clonic Convulsions
  • No Specific Antidote Known
  • Treatment should be Symptomatic and Supportive

Storage conditions

  • Store at a Temperature not Exceeding 30°C in a Dry Place
  • Protect from Light and Moisture
  • Keep out of Reach of Children

Chemical structure

  • Molecular formula: C17H19N3O3S
  • Chemical image url: https://medex.com.bd/storage/res/g-res-433-esomeprazole-chemical-structure-Tj2Jfp1VmPkRjNXznKqC.svg

Common questions

  • What is it: A proton pump inhibitor (PPI) used to treat gastroesophageal reflux disease (GERD), ulcers, and other conditions involving excessive stomach acid production
  • Common uses: Eases heartburn, relieves GERD symptoms, heals erosive esophagitis, prevents its recurrence, and aids in ulcer healing
  • Side effects: Common side effects include headache, diarrhea, nausea, gas, stomach pain, constipation, and dry mouth
  • Pregnancy and breastfeeding: No significant side effects noted, but consultation with a doctor is advised
  • Time to work: Generally starts working within a few hours of consumption
  • Quick tips:
    • Well-tolerated and provides long-term relief
    • Avoid late-night eating
    • Inform doctor about persistent digestive issues
    • Long-term use may affect bone health, follow doctor's recommendations for calcium and magnesium intake
    • Consult doctor for symptoms indicating a kidney problem

Related Brands