Ramoril 10 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ramipril |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Hypertension
- Congestive heart failure
- Acute myocardial infarction
- Glomerular nephropathy
- Cardiovascular risk reduction
Pharmacology
Blocks the conversion of angiotensin I to angiotensin II, decreases plasma angiotensin II, reduces vasopressor activity, and decreases aldosterone secretion
Dosage
- Adjustable according to patient tolerance and response
- Usual initial dose 1.25-2.5 mg once daily for hypertension
- 5 mg twice daily for congestive heart failure after myocardial infarction
- 2.5 mg once daily for Prevention of major cardiovascular events
Administration
- Tablets must be swallowed with liquid
- Can be taken before, during, or after a meal
Interaction
- May lead to hypotension and hyperkalemia with diuretics
- May increase lithium serum concentration when used concomitantly with lithium
- NSAIDs may reduce antihypertensive effect and cause renal function deterioration
Contraindications
- Hypersensitivity to ramipril or other ACE inhibitors
- History of angioedema
- Concomitant use with sacubitril/valsartan therapy
- Haemodynamically relevant renal artery stenosis
- Hypotensive or haemodynamically unstable states
- Concomitant use with aliskiren-containing medicines in certain patients
Side Effects
- Dizziness
- Headache
- Fatigue
- Asthenia
- Symptomatic hypotension
- Cough
- Nausea
- Vomiting
- Diarrhoea
- Rash
- Urticaria
- Oliguria
- Anxiety
- Amnesia
- Angioneurotic oedema
- Anaphylactic reactions
- Hyperkalaemia
Pregnancy & Lactation
- Must not be used during pregnancy
- Pregnancy must be avoided if treatment with ACE inhibitors is necessary
- Not recommended during breastfeeding
Precautions & Warnings
- Use with caution in patients with impaired renal function, hyperkalaemia, hypotension, and impaired hepatic function
Use in Special Populations
- Consider reduced initial dose for elderly patients
- Initiate treatment with close medical supervision for patients with hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Marked hypotension
- Bradycardia
- Electrolyte disturbances
- Renal failure
Therapeutic Class
Angiotensin-converting enzyme (ACE) inhibitors
Storage Conditions
Store at 30°C or below, protect from light, and keep out of the reach of children