Analac 60 mg/2 ml (IM/IV Injection)
2 ml ampoule: ৳ 95.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Moderate to severe acute post-operative pain management
- Ocular pain relief after surgery
- Decrease eye inflammation caused by seasonal allergies
Description
- Pyrrolo-pyrrole group NSAID
- Chemical name: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- Peripherally acting analgesic
- Highly protein bound
- Metabolized in the liver
- Excretion in the urine
Pharmacology
- Potent analgesic
- Inhibits cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet: Recommended dose of 10 mg every 4-6 hours
- Injection: IV bolus or IM administration
- Dosing based on age and body weight
- Maximum daily dosage limits
- Eye Drops: 1 drop in each eye 4 times daily
Interaction
- Increased side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with Beta Blockers
- Increased risk of renal impairment with ACE Inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- US FDA Pregnancy category: C
- Avoidance during pregnancy and lactation
- Assessing benefits versus risks
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, liver dysfunction
- Discontinue use in presence of corneal epithelial breakdown
- Avoid use with contact lenses
Therapeutic Class
- Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
- Dry place away from light and heat
- Keep out of reach of children