Imucort 6 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Polymyalgia rheumatica
- Systemic lupus erythematosus
- Dermatomyositis
- Mixed connective tissue disease
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anaemia
- Idiopathic thrombocytopenic purpura
- Acute and lymphatic leukaemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
Inhibits Phospholipase A2 enzyme, decreases release of certain immune system chemicals
Dosage & Administration
- Adults:
- Up to 120 mg/day for acute disorders
- Maintenance doses within the range of 3-18 mg/day for most conditions
- Titrate to the lowest effective dose for maintenance in other conditions
- Children:
- Doses usually lie in the range 0.25-1.5 mg/kg/day
- Deflazacort withdrawal: Dose reduction depends on relapse likelihood
Interaction
Metabolized in the liver; dose adjustment needed with liver enzyme inducers or inhibitors
Contraindications
- Hypersensitivity to any of the ingredients
- Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal issues
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Striae
- Telangiectasia
- Acne
- Myocardial rupture following recent Ml
- Thromboembolism
Pregnancy & Lactation
- Pregnancy: Crosses placenta; may increase risk of intrauterine growth retardation
- Nursing Mother: Excreted in breast milk; higher doses may cause adrenal suppression in infants
Precautions & Warnings
- Cardiac disease or congestive heart failure
- Hypertension
- Thromboembolic disorders
- Gastritis or oesophagitis
- Diverticulitis
- Ulcerative colitis
- Diabetes mellitus
- Osteoporosis
- Myasthenia gravis
- Renal insufficiency
- Emotional instability or psychotic tendency
- Epilepsy
- Liver failure
- Hypothyroidism and cirrhosis
- Ocular herpes simplex
Use in Special Populations
- Hepatic Impairment: Dose monitoring and adjustment needed
- Renal Impairment: No special precautions necessary
- Elderly: No special precautions necessary
Therapeutic Class
Glucocorticoids
Storage Conditions
Store below 25°C, protected from light & moisture, keep out of reach of children