Imucort 6 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Polymyalgia rheumatica
- Systemic lupus erythematosus
- Dermatomyositis
- Mixed connective tissue disease
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anaemia
- Idiopathic thrombocytopenic purpura
- Acute leukaemia
- Lymphatic leukaemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
- Anti-inflammatory action
- Inhibition of Phospholipase A2 enzyme
- Prostaglandin synthesis inhibition
- Immune system chemical release inhibition
- Immunosuppressive action
Dosage & Administration
- Up to 120 mg/day for acute disorders
- Maintenance doses within 3-18 mg/day for most conditions
- Titration to the lowest effective dose
- Specific doses for rheumatoid arthritis, bronchial asthma, juvenile chronic arthritis, and nephrotic syndrome
- Deflazacort withdrawal strategy
Interaction
- Metabolism in the liver
- Effects of liver enzyme inducers
- Effects of liver enzyme inhibitors
Contraindications
- Hypersensitivity to ingredients
- Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal issues
- Endocrine issues
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Striae
- Telangiectasia
- Acne
- Myocardial rupture
- Thromboembolism
Pregnancy & Lactation
- Crossing the placenta
- Increased risk of intrauterine growth retardation
- Excretion in breast milk
- Systemic effects in the infant
- Adrenal suppression in infants
Precautions & Warnings
- Caution and monitoring for cardiac disease or congestive heart failure
- Special caution for hypertension, thromboembolic disorders
- Risk of salt and water retention
- Special caution for gastritis, oesophagitis, diverticulitis, ulcerative colitis
- Caution with respect to diabetes mellitus, osteoporosis, myasthenia gravis, renal insufficiency
- Monitoring for emotional instability, psychotic tendency, and epilepsy
- Precaution for previous corticosteroid-induced myopathy
- Caution in cases of liver failure, hypothyroidism, cirrhosis, and ocular herpes simplex
Use in Special Populations
- Monitoring of blood levels in hepatic impairment
- No special precautions in renally impaired patients
- No special precautions in elderly patients
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Cool and dry storage below 25°C
- Protection from light and moisture
- Keep out of reach of children