Laxitol 10 gm/sachet (Oral Powder)

10 gm sachet: ৳ 12.00 (10's pack: ৳ 120.00)

Medicine Details

Indications

  • Chronic idiopathic constipation (CIC)
  • Acute and chronic portal systemic encephalopathy

Pharmacology

  • Consists of galactose and sorbitol
  • Not hydrolysed by the disaccharidases of the GIT
  • Increase in osmotic pressure in the colon
  • Virtually 100% bioavailable

Dosage & Administration

  • Can be mixed with hot or cold beverages, puddings etc.
  • Adjust dosage to obtain one daily bowel movement in constipated patients and two in patients with portal systemic encephalopathy
  • Dose adjustment according to patient's disease severity and response

Interaction

  • Avoid simultaneous administration with antacids and neomycin in cirrhotic patients with portal systemic encephalopathy
  • May increase potassium loss caused by other drugs
  • May enhance the risk of toxic effects of glycosides in patients receiving concomitant therapy

Contraindications

  • Known hypersensitivity to any ingredients of the preparation

Side Effects

  • May produce abdominal discomforts at the start of treatment such as flatulence, pain, cramps, or sensation of fullness
  • Occasional reports of nausea or anal pruritus

Pregnancy & Lactation

  • Minimally absorbed systemically following oral administration
  • Unknown fetal exposure and effects on breastfed infant or milk production

Precautions & Warnings

  • Elderly or debilitated patients receiving long-term treatment should have their serum electrolytes monitored regularly
  • Pre-existing fluid or electrolyte imbalance should be corrected before starting treatment
  • Hydrogen accumulation in the bowel following treatment
  • Not recommended in case of ileostomy or colostomy
  • Prolonged use without interruption should be avoided

Therapeutic Class

Osmotic purgatives

Storage Conditions

Store in a cool, dry place and away from light. Keep out of reach of children

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