Albrex 400 mg (Chewable Tablet)

Unit Price: ৳ 3.50 (50's pack: ৳ 175.00)

Medicine Details

Category Details
Generic Albendazole
Company Medimet pharmaceuticals ltd

Indications

  • Single infestations of hookworm (Ancylostoma, Necator)
  • Mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, hydatid

Description

  • Benzimidazole anthelmintic
  • Active against most nematodes and some cestodes
  • Treatment of intestinal nematode infections
  • Treatment of hydatid disease
  • Vermicidal, ovicidal, and larvicidal activity
  • Inhibitory effect on tubulin polymerization

Pharmacology

  • Broad spectrum anthelmintic
  • Vermicidal, ovicidal, and larvicidal activities
  • Blocks glucose uptake in susceptible helminths
  • Depletes energy level of helminths
  • Exerts anthelmintic effect by blocking tubulin polymerization
  • Extensively metabolized, probably in the liver

Dosage & Administration

  • 400 mg single dose for various infestations
  • 400 mg daily for 3 consecutive days for strongyloidiasis or taeniasis
  • 200 mg recommended single dose for children of 1-2 years
  • 400 mg twice daily for 28 days for hydatid disease
  • 15 mg/kg body weight daily for patients less than 60 kg

Interaction

  • No reported pharmacodynamic or pharmacokinetic interactions

Contraindications

  • Not normally used in neonates
  • Reduction of dose may be indicated in children weighing less than 10 kg
  • Avoid in pregnancy and lactation
  • No evidence for altering dose in renal, hepatic, or cardiac failure

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Changes in liver enzymes
  • Reversible alopecia
  • Rash
  • Fever
  • Blood disorders
  • Allergic shock
  • Convulsion and meningism

Pregnancy & Lactation

  • FDA Pregnancy category - C
  • Avoid in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Blood counts and liver function tests before and during treatment
  • Caution in breastfeeding
  • Constant medical supervision with regular monitoring in Echinococcosis treatment

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Keep in a dry place
  • Keep away from light and heat
  • Keep out of reach of children

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