Combigan 0.2%+0.5% (Ophthalmic Solution)
Medicine Details
Category | Details |
---|---|
Generic | Brimonidine tartrate timolol maleate |
Company | Allergan pharmaceuticals international ltd |
Indications
Reduction of elevated intraocular pressure in patients with glaucoma or ocular hypertension
Pharmacology
Comprised of Brimonidine Tartrate & Timolol Maleate, with dual mechanism of action to decrease aqueous humor production and increase uveoscleral outflow
Dosage & Administration
Instill 1 drop in the affected eye(s) twice daily
Interaction
No specific drug interaction studies conducted
Contraindications
Hypersensitivity to any component, bronchial asthma, severe chronic obstructive pulmonary disease, sinus bradycardia, second or third-degree atrioventricular block, overt cardiac failure, cardiogenic shock
Side Effects
Common side effects include allergic conjunctivitis, conjunctival folliculosis, conjunctival hyperaemia, eye pruritus, ocular burning or stinging
Pregnancy & Lactation
No well-controlled studies in pregnant women, possible risk to fetus, presence in human milk, decision on nursing should consider drug's importance to mother
Precautions & Warnings
May be absorbed systemically, potential cardiovascular and pulmonary adverse reactions, exercise caution in severe or unstable cardiovascular or pulmonary diseases
Use in Special Populations
- Safety and effectiveness in children below the age of 2 years have not been established
- No overall differences in safety or effectiveness between elderly and other adult patients
Therapeutic Class
Drugs for miotics and glaucoma
Storage Conditions
Store at a cool & dry place, protect from light, use within 30 days after first opening, keep out of the reach of children
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