Escap 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Esomeprazole
Company Synovia pharma plc
Also available as
Escap 40 mg capsule

Title

Escap 20 mg Capsule

Categories

  • Medicine
  • Health
  • Gastrointestinal Health

Description

Esomeprazole is a proton pump inhibitor used to relieve chronic heartburn, heal erosive esophagitis, maintain healing, eradicate Helicobacter pylori infection, treat Zollinger-Ellison Syndrome, and manage acid-related dyspepsia, duodenal & gastric ulcers.

Attributes

  • Indications:
    • Chronic heartburn relief
    • Healing of erosive esophagitis
    • Maintenance of healing of erosive esophagitis
    • Eradication of Helicobacter pylori infection
    • Treatment of Zollinger-Ellison Syndrome
    • Management of acid-related dyspepsia
    • Treatment of duodenal & gastric ulcers
  • Pharmacology:
    • Proton pump inhibitor
    • Specific inhibition of H+/K+-ATPase
    • Better acid control than racemic proton pump inhibitors
    • Peak plasma levels at approximately 1.5 hours after oral administration
    • Extensively metabolized in the liver
    • 97% bound to plasma proteins
    • Systemic bioavailability of approximately 90%
    • Protein binding constant over the concentration range
    • Plasma elimination half-life of approximately 1–1.5 hours
  • Dosage:
    • Healing of erosive esophagitis: 20 mg or 40 mg once daily for 4-8 weeks
    • Maintenance of healing of erosive esophagitis: 20 mg once daily
    • Symptomatic GERD: 20 mg once daily for 4 weeks
    • Helicobacter pylori eradication: Triple Therapy for 10 days
    • Zollinger-Ellison Syndrome: 20-80 mg once daily
    • Acid-related Dyspepsia: 20-40 mg once daily for 2-4 weeks
    • Duodenal ulcer: 20 mg once daily for 2-4 weeks
    • Gastric ulcer: 20-40 mg once daily for 4-8 weeks
    • IV Injection or IV infusion for different patient categories
  • Administration:
    • Tablet or capsule should be swallowed whole and taken one hour before a meal
    • Oral suspension should be taken with water and administered through a nasogastric or gastric tube if needed
    • IV injection should be administrated intravenously over a period of at least 3 minutes
  • Interaction:
    • Metabolized by CYP2C19 and CYP3A4
    • Unlikely to inhibit various CYP enzymes
    • Potential interference with drugs where gastric pH is important for bioavailability
  • Contraindications:
    • Known hypersensitivity to any of the formulation
  • Side Effects:
    • Headache
    • Diarrhoea
    • Nausea
    • Flatulence
    • Abdominal pain
    • Constipation
    • Dry mouth
  • Pregnancy & Lactation:
    • No adequate and well-controlled studies in pregnant women
    • Animal studies revealed no teratogenic effects
    • Excretion in milk not studied
  • Precautions & Warnings:
    • Symptomatic response does not preclude the presence of gastric malignancy
    • Instructions for patients
    • Use in Special Populations
  • Overdose Effects:
    • Acute toxicity in rats
    • No reports of overdose with Escap
  • Storage Conditions:
    • Store at a temperature not exceeding 30°C
    • Protect from light and moisture
    • Keep out of reach of children
  • Chemical Structure:
    • Molecular Formula: C17H19N3O3S
  • Common Questions:
    • Uses of Escap 20 mg Capsule
    • Side effects
    • Pregnancy and breastfeeding
    • Time for Escap 20 mg Capsule to work
    • Quick Tips

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