Expres 10 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)

Strip Price: ৳ 120.00

Medicine Details

Escitalopram is an orally administered selective serotonin reuptake inhibitor (SSRI)
Escitalopram is the pure S-enantiomer of the racemic bicyclic phthalate derivative citalopram
Escitalopram is at least 100 fold more potent than the R-enantiomer with respect to inhibition of 5-HT reuptake
Escitalopram has no or very low affinity for serotonergic or other receptors including alpha- and beta-adrenergic, Dopamine, Histamine, Muscarinic, and benzodiazepine receptors

Safety of daily doses above 20 mg has not been demonstrated
Usual dosage for major depressive episodes is 10 mg once daily, may be increased to a maximum of 20 mg daily
Usual dosage for panic disorder is 5 mg for first week, before increasing to 10 mg daily, may further increase to a maximum of 20 mg daily
Usual dosage for social anxiety disorder is 10 mg once daily, dose may be decreased to 5 mg or increased to a maximum of 20 mg daily
Usual dosage for generalised anxiety disorder is 10 mg once daily, may be increased to a maximum of 20 mg daily
Usual dosage for obsessive-compulsive disorder is 10 mg once daily, may be increased to a maximum of 20 mg daily

Escitalopram should generally be administered once daily, morning or evening, with or without food

SSRI or related antidepressants should not be started until 2 weeks after stopping an MAOI
An MAOI should not be started until at least a week after an SSRI or related antidepressant has been stopped (2 weeks in the case of paroxetine and sertraline, at least 5 weeks in the case of fluoxetine)

Escitalopram is contraindicated in patients with known hypersensitivity to Escitalopram or Citalopram or any of the inactive ingredients of the drug product
Concomitant use of escitalopram in patients taking monoamine oxidase/pimozide is contraindicated

Less sedating and have fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants
Side-effects of the SSRIs include gastrointestinal effects, anorexia with weight loss or increased appetite and weight gain, hypersensitivity reactions, dry mouth, nervousness, anxiety, headache, insomnia, tremor, dizziness, asthenia, hallucinations, drowsiness, convulsions, galactorrhoea, sexual dysfunction, urinary retention, sweating, hypomania or mania, movement disorders and dyskinesias, visual disturbances

Potential risks and benefits of treatment should be carefully considered when treating a pregnant woman with Escitalopram during the third trimester
Excreted in human breast milk, decision whether to continue or discontinue either nursing or Escitalopram therapy should take into account the risk of citalopram exposure for the infant and the benefits of Escitalopram treatment for the mother

SSRIs should be used with caution in patients with epilepsy, history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, concomitant use of drugs that increase risk of bleeding, history of bleeding disorders, hepatic and renal impairment

Elderly patients (>65 years of age) should start with an initial dosage of 5 mg once daily, may be increased to 10 mg daily
Expres should not be used in the treatment of children and adolescents under the age of 18 years
Dosage adjustment is not necessary in patients with mild or moderate renal impairment, caution advised in patients with severely reduced renal function
An initial dose of 5 mg daily for the first two weeks of treatment is recommended in patients with mild or moderate hepatic impairment, depending on individual patient response, the dose may be increased to 10 mg daily
For patients who are known to be poor metabolisers with respect to CYP2C19, an initial dose of 5 mg daily during the first two weeks of treatment is recommended, depending on individual patient response, the dose may be increased to 10 mg daily

Symptoms seen in a reported overdose of escitalopram include symptoms mainly related to the central nervous system, the gastrointestinal system, the cardiovascular system, and electrolyte/fluid balance conditions
There is no specific antidote, general symptomatic supportive measures are recommended