Unipril 5 mg (Tablet)
Unit Price: ৳ 8.07 (3 x 10: ৳ 242.10)
Strip Price: ৳ 80.70
Medicine Details
| Category | Details |
|---|---|
| Generic | Ramipril |
| Company | Acme laboratories ltd |
| Also available as |
Title
Unipril Medicine
Categories
- Hypertension
- Congestive heart failure
- Myocardial infarction
- Cardiovascular risk reduction
Description
Unipril is an angiotensin converting enzyme (ACE) inhibitor used to lower blood pressure, manage congestive heart failure, prevent major cardiovascular events, and reduce the risk of stroke, myocardial infarction and death from cardiovascular events.
Dosage Range
1.25 mg - 20 mg daily
Color Options
- White
Dosage Form
Tablet
Packaging Options
- Bottle
- Blister pack
Pharmacology
- Blocks angiotensin I conversion
- Decreases plasma angiotensin II
- Reduces vasopressor activity
- Decreases aldosterone secretion
Administration
Must be swallowed with liquid; can be taken before, during, or after a meal
Interaction Warnings
- Concomitant use with diuretics may lead to serious hypotension and hyperkalemia
- Concomitant therapy with lithium may increase serum lithium concentration
- NSAIDs may reduce antihypertensive effect
Contraindications
- Hypersensitivity to ramipril or other ACE inhibitors
- History of angioedema
- Presence of haemodynamically relevant renal artery stenosis
- Use of aliskiren-containing medicines in patients with diabetes or moderate to severe renal impairment
Side Effects
- Dizziness
- Headache
- Fatigue
- Asthenia
- Symptomatic hypotension
- Cough
- Nausea
- Vomiting
- Diarrhoea
- Rash
- Urticaria
- Hyperkalaemia
Pregnancy & Lactation
Must not be used during pregnancy; not recommended during breastfeeding
Precautions
- Use with caution in patients with impaired renal function, hyperkalaemia, hypotension, and impaired hepatic function
Special Population Uses
- Elderly: Consider reduced initial dose
- Hepatic impairment: Initiate treatment under close medical supervision
- Renal impairment: Adjust dose according to creatinine clearance
Overdose Effects
- Excessive peripheral vasodilatation
- Bradycardia
- Electrolyte disturbances
- Renal failure
Storage Conditions
Store at 30°C or below; protect from light; keep out of the reach of children