Qpine 200 mg (Tablet)
Unit Price: ৳ 18.05 (3 x 10: ৳ 541.50)
Strip Price: ৳ 180.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | Synovia pharma plc |
| Also available as |
Indications
- Treatment of Acute and chronic psychoses
- Treatment of schizophrenia
- Treatment of Bipolar Disorder
- Maintenance treatment of bipolar I disorder
- Prevention of recurrence of manic, depressive or mixed episodes
Pharmacology
- Belongs to dibenzothiazepine derivatives
- Antagonist at multiple neurotransmitter receptors in the brain
- No appreciable affinity at cholinergic muscarinic and benzodiazepine receptors
- Mechanism of action is unknown
- Efficacy in schizophrenia is mediated through a combination of dopamine D2 and serotonin 5HT2 antagonism
Dosage & Administration
- Administered twice daily
- Can be administered with or without food
- Dosage titrated based on clinical response and tolerability
- Recommended dosage range for different conditions
Interaction
- Caution with medicines causing electrolyte imbalance or increasing QT interval
- Increased clearance when used concomitantly with thioridazine, carbamazepine, and phenytoin
Contraindications
- Contra-indicated in patients who are hypersensitive to it
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Elevations in serum triglyceride levels
- Weight gain
- Decreased haemoglobin
- Extrapyramidal symptoms
Pregnancy & Lactation
- Safety and efficacy during human pregnancy not established
- Use during pregnancy only if benefits justify the potential risks
- Avoid breastfeeding while taking it
Precautions & Warnings
- Risk of suicidal thoughts and self-harm
- Caution in patients with known cardiovascular or cerebrovascular disease
- Caution in patients with a history of seizures
- Consideration of dose reduction or discontinuation if signs of tardive dyskinesia appear
- Caution in patients with a family history of QT prolongation
- Possible occurrence of neutropenia, hyperglycemia, and diabetes mellitus
Use in Special Populations
- Caution in the elderly
- Not indicated for use in children and adolescents below 18 years of age
Overdose Effects
- Survival reported in acute overdoses of up to 30 grams
- No specific antidote
- Intensive care procedures recommended
- Close medical supervision and monitoring required
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of the sight and reach of children
- Do not use after the expiry date
- Store in a cool, dry place away from light