Sperdal 1 mg/ml (Oral Solution)

100 ml bottle: ৳ 300.00

Medicine Details

Category Details
Generic Risperidone oral
Company Synovia pharma plc
Also available as
Sperdal 1 mg tablet Sperdal 2 mg tablet Sperdal 4 mg tablet

Indications

  • Acute and chronic psychoses
  • Mania
  • Schizophrenia

Pharmacology

Selective monoaminergic antagonist

Dosage & Administration

  • Psychoses:
    • 2 mg in 1-2 divided doses on 1st day then 4 mg in 1-2 divided doses on second day
    • Usual dose range 4-6 mg daily
    • Elderly initially 1 mg daily in two divided doses increased in steps of 1-2 mg twice daily
    • Child under 15 years not recommended
  • Mania:
    • Initially 2 mg once daily increased if necessary in step of 1 mg daily
    • Usual dose range 1-6 mg daily
    • Elderly initially 1 mg daily in two divided doses increased in steps of 1-2 mg twice daily
  • Schizophrenia:
    • Administered at 1 mg BID initially, with increases in increments of 1 mg BID on the second and third day, as tolerated, to a target dose of 3 mg BID by the third day
    • Further dosage adjustments, if indicated, should generally occur at intervals of not less than 1 week
    • Small dose increments/decrements of 1-2 mg are recommended for dosage adjustments

Interaction

May antagonize the effects of levodopa and dopamine agonists, reduces plasma clearance with Carbamazepine, may decrease the clearance with Clozapine, may enhance the effects of certain antihypertensives

Contraindications

Known hypersensitivity to the product

Side Effects

  • Insomnia
  • Agitation
  • Anxiety
  • Headache
  • Drowsiness
  • Impaired concentration
  • Fatigue
  • Blurred vision
  • Constipation
  • Nausea and vomiting
  • Dyspepsia
  • Abdominal pain
  • Hyperprolactinaemia
  • Urine incontinence
  • Tachycardia
  • Hypertension
  • Edema
  • Rash
  • Rhinitis
  • Cerebrovascular accident
  • Neurtropenia
  • Thrombocytopenia

Pregnancy & Lactation

Not established for use during human pregnancy, excreted in human breast milk

Precautions & Warnings

  • Preexisting cardiovascular diseases
  • Discontinue use if signs and symptoms of tardive dyskinesia occur
  • Renal and hepatic impairment
  • Elderly
  • Epilepsy
  • Parkinson's disease
  • Pregnancy

Therapeutic Class

Atypical neuroleptic drugs

Storage Conditions

Do not store above 30°C, keep away from light and out of the reach of children

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