Giran 16 mg (Tablet)

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Candesartan cilexetil
Company Aristopharma ltd
Also available as

Indications

  • Hypertension
  • Heart failure with impaired left ventricular systolic function

Pharmacology

  • Candesartan Cilexetil is an ester prodrug
  • Active form is Candesartan
  • Blocks angiotensin II receptor
  • Blocks vasoconstrictor and aldosterone-secreting effects

Dosage & Administration

  • Initial dose for hypertension: 8 mg once daily
  • Titration for hypertension: max 32 mg once daily
  • Initial dose for heart failure: 4 mg once daily
  • Titration for heart failure: target dose of 32 mg once daily

Interaction

  • No significant drug interactions reported
  • Not metabolized by cytochrome P-450 system

Contraindications

  • Hypersensitivity to any component
  • Not recommended during pregnancy and breastfeeding
  • Cholestasis

Side Effects

  • Symptomatic hypotension
  • Hyperkalemia
  • Angioedema
  • Vertigo
  • Headache
  • Hepatitis
  • Blood disorders
  • Rash
  • Urticaria

Pregnancy & Lactation

  • Discontinue in pregnancy
  • Can be used in lactation

Precautions & Warnings

  • Use with caution in renal artery stenosis
  • Monitoring of plasma-potassium concentration advised

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients

Therapeutic Class

  • Angiotensin II receptor blocker

Storage Conditions

  • Store in a cool & dry place
  • Protect from light and moisture

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