Freegest 10 mg (Tablet)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Montelukast sodium
Company Biopharma limited
Also available as
Freegest 4 mg chewable tablet Freegest 5 mg chewable tablet

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Selective and orally active leukotriene receptor antagonist
  • Inhibition of the cysteinyl leukotriene receptor (CysLT1)
  • Correlation with the pathophysiology of asthma & allergic rhinitis

Dosage & Administration

  • Dosage for adults and adolescents 15 years of age and older: Montelukast 10 mg tablet once daily
  • Dosage for pediatric patients 6 to 14 years of age: Montelukast 5 mg tablet once daily
  • Dosage for pediatric patients 2 years to 5 years of age: Montelukast 4 mg tablet once daily
  • Montelukast 4 mg oral granules once daily for pediatric patients 6 months to 5 years of age
  • No dosage adjustment for hepatic insufficiency
  • No dosage adjustment for renal insufficiency
  • Similar pharmacokinetic profile and oral bioavailability in elderly and younger adults

Interaction

  • No apparent increase in adverse reactions when administered with other therapies routinely used in the prophylaxis and chronic treatment of asthma
  • No clinically important effects on the pharmacokinetics of certain drugs at recommended clinical dose
  • Used concomitantly with a wide range of commonly prescribed drugs in clinical studies without evidence of clinical adverse interactions
  • Phenobarbital decreased the AUC of Freegest by approximately 40%
  • Clinical monitoring required when potent cytochrome P450 enzyme inducers are co-administered

Contraindications

  • Hypersensitivity to any component of this product

Side Effects

  • Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
  • Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor

Pregnancy & Lactation

  • Crosses the placenta following oral dosing in rats and rabbits
  • Use during pregnancy only if clearly needed
  • Caution should be exercised when given to a nursing mother

Precautions & Warnings

  • Not indicated for use in the reversal of bronchospasm in acute asthma attacks
  • Appropriate rescue medication should be available
  • Continued therapy during acute exacerbations of asthma
  • Should not be abruptly substituted for inhaled or oral corticosteroids
  • Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
  • Caution for patients with known aspirin sensitivity

Overdose Effects

  • No adverse experiences in the majority of overdosage reports
  • Usual supportive measures recommended in the event of overdose

Therapeutic Class

  • Leukotriene receptor antagonists

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S
  • Chemical Structure visual available

Common Questions about Freegest 10 mg Tablet

  • Description of Freegest 10 mg Tablet
  • Use for treating asthma or allergic rhinitis
  • Time for effect to be observed
  • Duration of effect
  • Administration with or without food
  • Pregnancy warnings
  • General instructions for usage

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