Onstar ODT 8 mg (Dispersible Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Biopharma limited |
| Also available as |
Therapeutic Class
- Anti-emetic drugs
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Description
- Orally dissolving film
- Applied on top of the tongue
- Dissolves within 20 seconds
Pharmacology
- Selective blocking agent of the serotonin 5-HT3 receptor type
- Antagonism of 5HT3 receptors on neurons in peripheral and central nervous system
Dosage
- Multiple dosage options for adults and pediatric patients
- Different doses for chemotherapy-induced, radiotherapy-induced, and postoperative nausea and vomiting
Administration
- Step by step guidance for administration of oral soluble film
- No water required for dissolution or swallowing
Interaction
- Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes
- May be affected by inducers or inhibitors of these enzymes
Contraindications
- Hypersensitivity to the drug or any of its components
- Concomitant use of apomorphine
Side Effects
- Frequently reported adverse events such as headache, constipation, and diarrhea
- Rare cases of anaphylaxis, bronchospasm, and tachycardia
Pregnancy & Lactation
- No evidence of impaired fertility or harm to the fetus in animal studies
- Caution advised when administered to nursing women
Precautions & Warnings
- Hypersensitivity reactions reported in patients hypersensitive to other 5-HT3 receptor antagonists
- Not a drug that stimulates gastric or intestinal peristalsis
Use in Special Populations
- Dosage adjustment for patients with impaired renal function
- Dosage adjustment for patients with impaired hepatic function
- Limited information available for pediatric patients 4 years of age or younger
Storage Conditions
- Recommended to store at temperature not exceeding 30°C
- Protect from light and moisture