Copadox 400 mg (Tablet)

Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)

Strip Price: ৳ 90.00

Medicine Details

Category	Details
Generic	Doxophylline
Company	Somatec pharmaceuticals ltd
Also available as	Copadox 200 mg tablet

Title

Copadox Tablet

Description

Copadox Tablet is used to treat bronchial asthma, bronchospasm, chronic obstructive pulmonary disease (COPD), and pulmonary disease with spastic bronchial component. It is a bronchodilator that selectively inhibits phosphodiesterase 4 to relax bronchial smooth muscle. The dosage varies for elderly, adults, and children above and below 12 years of age. The drug has contraindications for individuals with known hypersensitivity to xanthine derivatives and in patients with acute myocardial infarction, hypotension, and during lactation. Possible side effects include nausea, vomiting, headache, and tachycardia, with severe effects in case of overdose. It is contraindicated during pregnancy and lactation. Storage conditions require keeping the tablet in a dry place away from light and heat.

Dimensions

13mm x 8mm x 5mm

Color options

White

Functions

Bronchodilation
Relaxation of bronchial smooth muscle

Materials

Doxophylline
Xanthine derivatives

Technical specifications

Active ingredient: Doxophylline
Pharmacological class: Methyl xanthine derivatives
Recommended dosage:
- Elderly: 200 mg tablet two or three times daily
- Adults: 400 mg tablet two or three times daily
- Children:
  - >12 years: 10 ml syrup or 200 mg tablet two or three times daily
  - 6-12 years: 6-9 mg/kg body weight two times daily

Design elements

Tablet form
Coated tablet

Usability features

Prescription-only
Suitable for specialist physician prescription

Interaction

Restricted combinations:
- Other xanthine preparations
Cautions:
- Limit consumption of beverages and food containing caffeine
- Exercise caution with ephedrine or other sympathomimetic drugs
Impact on hepatic clearance:
- Reduced by:
  - Erythromycin
  - TAO
  - Lincomycin
  - Clindamycin
  - Allopurinol
  - Cimetidine
  - Influenza vaccine
  - Propanolol
- Increased by:
  - Phenytoin
  - Other anticonvulsants
  - Cigarette smoking

Contraindications

Known hypersensitivity to the drug or other xanthine derivatives
Acute myocardial infarction
Hypotension
During lactation

Side effects

Nausea
Vomiting
Epigastric pain
Headache
Tachycardia
Insomnia
Hyperglycemia
Albuminuria
Severe cardiac arrhythmias
Tonic-clonic seizure

Pregnancy lactation

Effects on pregnancy: Animal tests have shown no interference with pre and postnatal growth
Clinical evaluation: Use during pregnancy should be evaluated carefully case by case on the basis of the risk-benefit ratio
Contraindicated during lactation: 1

Precautions warnings

Factors reducing clearance:
- Age
- Congestive cardiac decompensation
- Chronic obstructive pulmonary disease
- Severe liver disease
- Concomitant infections
Cautions for use:
- Cardiac disease
- Hypertension
- Elderly patients
- Severe hypoxemia
- Hyperthyroidism
- Liver disease
- Peptic ulcer
- Renal impairment
Monitoring recommendations: In case of factors that may influence the clearance of xanthine derivatives, monitoring of the concentration of the blood levels of the drug is recommended for the control of the therapeutic range

Overdose effects

Severe cardiac arrhythmias and tonic-clonic seizure may occur, requiring discontinuation of the treatment and, if necessary, resume at lower doses after all signs and symptoms of toxicity have subsided