Axofyl 200 mg (Tablet)

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Doxophylline
Company Orion pharma ltd
Also available as

Indications

  • Bronchial asthma
  • Bronchospasm
  • Chronic obstructive pulmonary disease (COPD)
  • Pulmonary disease with spastic bronchial component

Pharmacology

  • Selective inhibition of phosphodiesterase 4
  • Relaxation of bronchial smooth muscle
  • Decreased affinities toward adenosine A1 and A2 receptors
  • Inhibition of platelet activating factor (PAF) and leukotriene production

Dosage & Administration

  • Recommended dosage for elderly, adults, and children
  • Different dosage for different age groups
  • Special release tablet for specific daily dose

Interaction

  • Avoid concurrent administration with other xanthine preparations
  • Caution with caffeine-containing beverages and food
  • Exercise caution with sympathomimetic drugs
  • Potential drug interactions with erythromycin, TAO, lincomycin, etc.

Contraindications

  • Hypersensitivity to the drug or other xanthine derivatives
  • Acute myocardial infarction
  • Hypotension
  • Lactation

Side Effects

  • Nausea
  • Vomiting
  • Epigastric pain
  • Headache
  • Insomnia
  • Tachycardia
  • Tachypnea
  • Rare cases of hyperglycemia or albuminuria
  • Severe effects in case of overdose

Pregnancy & Lactation

  • Animal tests show no interference with pre and postnatal growth
  • Insufficient clinical evidence during pregnancy
  • Contraindicated during lactation

Precautions & Warnings

  • Factors affecting hepatic clearance of xanthine derivatives
  • Caution in patients with cardiac disease, hypertension, elderly, severe hypoxemia, etc.
  • Monitoring of blood levels in certain patient groups

Overdose Effects

  • Severe cardiac arrhythmias
  • Tonic-clonic seizure
  • No specific antidote

Therapeutic Class

  • Bronchodilator
  • Methyl xanthine derivatives

Storage Conditions

  • Dry place away from light and heat
  • Keep out of reach of children
  • Use only on prescription of a specialist physician

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