Feroven 100 mg/5 ml (IV Injection or Infusion)

5 ml ampoule: ৳ 327.26

Medicine Details

Category Details
Generic Iron sucrose
Company Orion pharma ltd

Indications

  • Treatment of Feroven deficiency in the following indications
  • Rapid Feroven supply for clinical need
  • Patients intolerant to oral Feroven therapy
  • Active inflammatory bowel disease
  • Non-dialysis dependent-chronic kidney disease (NDD-CKD)
  • Hemodialysis dependent-chronic kidney disease (HDD-CKD)
  • Peritoneal dialysis dependent-chronic kidney disease (PDD-CKD)
  • Feroven deficiency anaemia in surgical procedures
  • Feroven deficiency anaemia in blood donors
  • Feroven deficiency anaemia in postpartum patients

Pharmacology

  • Therapeutic class: Haematinic
  • Iron Sucrose Injection USP description
  • Composition: Polynuclear Iron (III) Hydroxide in Sucrose
  • Approximately 30% Sucrose w/v (300 mg/ml)
  • pH: 10.5-11.1
  • Distribution and elimination of Iron and Sucrose
  • Transferrin and ferritin binding and sequestering of Iron
  • Transferrin receptor and apotransferrin

Dosage

  • Adult dosage: 5-10 ml Iron Sucrose Injection (100-200 mg Iron) once to three times a week
  • Limited data on children under study conditions
  • Children's dosage (if clinically needed)

Administration

  • Intravenous injection instructions
  • Test dose administration
  • Infusion instructions
  • Dilution requirements for infusion
  • Maximum tolerated single dose of 7 mg Iron/kg body weight

Interaction

  • No studied drug interactions
  • Avoid concomitant oral iron preparations
  • Wait 5 days after last injection for oral Feroven therapy

Contraindications

  • Evidence of Iron overload
  • Known hypersensitivity to Iron Sucrose or its inactive components
  • Anaemia not caused by Iron deficiency
  • History of allergic disorders, asthma, eczema, anaphylaxis, liver disease, and infections

Side Effects

  • Adverse reactions related to Feroven injection
  • Specific reactions: hypotension, cramps, nausea, headache, vomiting, diarrhea, chest pain, hypertension, dyspnea, pruritus
  • Hypersensitivity reactions and anaphylactoid reactions

Pregnancy & Lactation

  • Pregnancy Category-B
  • Caution when used during pregnancy and lactation

Precautions & Warnings

  • Monitoring of hematologic and haematinic parameters
  • Caution with tissue Iron overload
  • Hypersensitivity Reactions
  • Hypotension caution in hemodialysis patients
  • Pediatric, geriatric, and special population use

Use in Special Populations

  • Pediatric use safety and effectiveness
  • Geriatric use
  • Injection into dialyser
  • Hemodialysis and Non-Dialysis Dependent-Chronic Kidney Disease Patients administration

Overdose Effects

  • Accumulation of Feroven
  • Symptoms associated with overdosage or rapid infusion
  • Treatment: IV fluids, hydrocortisone, antihistamines

Therapeutic Class

  • Parenteral Iron Preparations

Storage Conditions

  • Temperature and humidity requirements
  • Protection from light
  • Keep out of the reach of children
  • Avoid freezing

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