Vertex 500 mg/vial (IM Injection)
500 mg vial: ৳ 130.39
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Orion pharma ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Potent bactericidal activity
- Broad-spectrum antibiotic
- Interferes with bacterial cell wall synthesis
- Stable in the presence of beta lactamases
- Long plasma elimination half-life
- High degree of stability
Dosage
- Usual adult dose of 1 to 2 gm by intravenous or intramuscular administration
- Maximum adult dose of 4 gm/day
- Usual infant and child dose of 50 to 75 mg/kg intravenous or intramuscular administration
- Maximum infant and child dose of 2 gm/day
- Duration of therapy of 4 to 14 days
Administration
- Preparation of solutions for intramuscular/intravenous injections
- Administered over 2-4 minutes
- Patient tolerance test before starting treatment
- Freshly reconstituted solution recommended
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects including diarrhea, nausea, vomiting
- Cutaneous reactions including rash, pruritus, urticaria
- Hematologic reactions including eosinophilia, thrombocytopenia
- Hepatic reactions including elevations of SGOT or SGPT, bilirubinemia
- CNS reactions including nervousness, confusion, headache
- Local phlebitis following intravenous administration
Pregnancy & Lactation
- Safety in human pregnancy not established
- Caution advised during lactation
Precautions & Warnings
- Possibility of anaphylactic shock
- Monitoring of blood picture during prolonged treatment
Use in Special Populations
- Not for neonates if premature or newborn
Overdose Effects
- No specific antidote
- Symptomatic treatment advised
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place below 30°C
- Keep away from light and moisture
- Keep out of reach of children