Orlev 500 mg (Tablet)
Unit Price: ৳ 15.01 (20's pack: ৳ 300.28)
Medicine Details
| Category | Details |
|---|---|
| Generic | Levofloxacin hemihydrate |
| Company | Orion infusion ltd |
| Also available as |
Indications
- Treatment of mild, moderate, and severe infections
- Acute maxillary sinusitis
- Acute bacterial exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Uncomplicated & complicated urinary tract infections
- Acute pyelonephritis
- Uncomplicated & complicated skin and soft tissue infections
- Enteric infections
- Antibacterial action against a wide range of microorganisms
Description
- Synthetic broad-spectrum third-generation fluoroquinolone derivative antibacterial agent
- Chiral fluorinated carboxyquinolone
Pharmacology
- Inhibition of bacterial topoisomerase IV and DNA gyrase
- Exerts antibacterial action by inhibiting enzymes required for DNA replication, transcription, repair, and recombination
- In vitro activity against a wide range of gram-negative and gram-positive microorganisms
Dosage
- Available in 250 mg, 500 mg, and 750 mg tablets
- Can be administered without regard to food
- Oral solution to be taken 1 hour before or 2 hours after eating
- Intravenous infusion for injection administration
- Specific doses for different infections in adults and children
- Sequential therapy (intravenous to oral) may be instituted at the discretion of the physician
Administration
- Instructions for the use of Levofloxacin infusion
- Specific guidelines for administration of the injection
Interaction
- Avoid co-administration with solutions containing multivalent cations
- Reduced absorption with antacids, iron, and adsorbents
- Increased risk of CNS stimulation with NSAIDs
- Increased risk of bleeding with warfarin
Contraindications
- Hypersensitivity to levofloxacin or quinolone antimicrobial agents
Side Effects
- Well-tolerated with few side effects
- Risk of retinal detachment
- Common side effects include nausea, vomiting, diarrhea, abdominal pain, and flatulence
- Rare occurrence of phototoxicity
- Rare side effects include tremors, depression, anxiety, and confusion
Pregnancy & Lactation
- Not recommended for use during pregnancy or nursing
Precautions & Warnings
- Administered by slow intravenous infusion
- Adequate hydration to avoid concentrated urine
- Dose adjustment in the presence of renal insufficiency
Overdose Effects
- Low potential for acute toxicity
- Stomach should be emptied in case of acute overdosage
- Patients should be kept under observation and hydration maintained
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Store below 30°C temperature, away from light and moisture
- Keep out of the reach of children