Cinagen-D 0.5%+0.1% (Ophthalmic Solution)

5 ml drop: ৳ 200.00

Medicine Details

Category Details
Generic Moxifloxacin hydrochloride dexamethasone
Company Navana pharmaceuticals ltd

Indications

  • Treatment of eye infections
  • Prevention of inflammation after eye surgery
  • Treatment of bacterial infection after eye surgery

Composition

  • Moxifloxacin 5 mg per ml
  • Dexamethasone 1 mg per ml

Mode of action

  • Moxifloxacin inhibits topoisomerase II and IV
  • Dexamethasone is anti-allergic and anti-exudative

Dosage & Administration

  • Instill 1 drop 4 times a day for prevention of infection and post-surgical ocular inflammation
  • Instill the medication immediately after eye surgery for cataract surgery
  • Instill the medication at least 15 minutes after ocular surgery for patients undergoing LASIK refractive surgery
  • Instill 1 drop 4 times a day for up to 7 days in eye infections caused by susceptible microorganisms

Contraindications

  • Hypersensitivity to other quinolones
  • Glaucoma
  • Ocular disease causing thinning of the cornea or sclera
  • Inflammation in the eye caused by virus, fungi or mycobacteria
  • Epithelial herpes simplex keratitis
  • Mycobacterial infection of the eye
  • Fungal diseases of ocular structures

Side Effects

  • Conjunctivitis
  • Decreased visual acuity
  • Dry eye
  • Keratitis
  • Ocular discomfort
  • Hyperemia
  • Pain
  • Subconjunctival hemorrhage
  • Tearing
  • Visual acuity & field defects
  • Cataract formation
  • Secondary ocular infection following suppression of host response
  • Perforation of the globe

Pregnancy & Lactation

  • Use during pregnancy only if potential benefit justifies potential risk to the fetus
  • Caution advised when used by nursing women

Precautions & Warnings

  • Discontinue use if allergic reaction occurs
  • Prolonged steroid use may result in ocular hypertension and/or glaucoma
  • Routine evaluation of intraocular pressure
  • Perforations have been known to occur with use of topical corticosteroids in diseases causing thinning of the cornea or sclera
  • Steroids may mask or enhance existing infection in acute purulent conditions of the eye

Use in Special Populations

  • No change in dosage required in elderly patients
  • Efficacy and safety not established in pediatric patients

Overdose Effects

  • No information available on overdosage

Therapeutic Class

  • Ophthalmic steroid preparations

Storage Conditions

  • Store in a cool place below 30°C
  • Protect from light
  • Once opened, use within 28 days and store at room temperature up to 30°C
  • Discard after 28 days
  • Keep out of reach of children

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