Filodox 200 mg (Tablet)
Unit Price: ৳ 6.00 (6 x 10: ৳ 360.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
- Bronchial asthma
- Bronchospasm
- Chronic obstructive pulmonary disease (COPD)
- Pulmonary disease with spastic bronchial component
Pharmacology
- Novel bronchodilator
- Selective inhibition of phosphodiesterase 4
- Presence of dioxolane group
- Relaxes bronchial smooth muscle
- Decreased affinities toward adenosine A1 and A2 receptors
- Inhibition of platelet activating factor (PAF)
- Inhibition of leukotriene production
Dosage and administration
- Elderly dosage: 200 mg tablet two or three times daily
- Adults dosage: 400 mg tablet two or three times daily
- Children dosage (>12 years of age): 10 ml syrup or 200 mg tablet two or three times daily
- Children dosage (6-12 years of age): 6-9 mg/kg body weight two times daily
Interaction
- Avoid administering with other xanthine preparations
- Limit consumption of caffeine-containing beverages and food
- Exercise caution when administering with ephedrine or other sympathomimetic drugs
- Caution with concurrent administration of certain drugs
Contraindications
- Known hypersensitivity to the drug or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- During lactation
Side effects
- Nausea
- Vomiting
- Epigastric pain
- Headache
- Irritability
- Insomnia
- Tachycardia
- Extrasystoles
- Tachypnea
- Hyperglycemia
- Albuminuria
- Severe cardiac arrhythmias
- Tonic-clonic seizure
Pregnancy and lactation
- Animal tests show no interference with pre and postnatal growth
- Lack of sufficient clinical evidence on effects during pregnancy
- Use during pregnancy should be carefully evaluated based on risk-benefit ratio
- Contraindicated during lactation
Precautions and warnings
- Factors that may reduce hepatic clearance
- Caution in patients with cardiac disease, hypertension, and elderly
- Monitoring of drug blood levels in certain cases
- Caution in patients with severe hypoxemia, hyperthyroidism, and liver disease
- No risk of addiction or dependence
Overdose effects
- Severe cardiac arrhythmias
- Tonic-clonic seizure
- Symptomatic treatment of cardiovascular collapse
Therapeutic class
- Bronchodilator
- Methyl xanthine derivatives
Storage conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
- Use only on prescription of specialist physician