Filodox 400 mg (Tablet)
Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
- Bronchial asthma
- Bronchospasm
- Chronic obstructive pulmonary disease (COPD)
- Pulmonary disease with spastic bronchial component
Pharmacology
- Doxophylline as a novel bronchodilator
- Structural difference from Theophylline
- Selective inhibition of phosphodiesterase 4
- Relaxation of bronchial smooth muscle
- Decreased affinities toward adenosine A1 and A2 receptors
- Inhibition of platelet activating factor (PAF)
- Inhibition of leukotriene production
Dosage & Administration
- Elderly: 200 mg tablet two or three times daily
- Adults: 400 mg tablet two or three times daily
- Children >12 years of age: 10 ml syrup or 200 mg tablet two or three times daily
- Children 6-12 years of age: 6-9 mg/kg body weight two times daily
- Special release tablet for 400 mg daily dose
Interaction
- Not to be administered with other xanthine preparations
- Limit consumption of caffeine-containing beverages and food
- Caution with ephedrine or other sympathomimetic drugs
- Caution with concurrent administration of various drugs
Contraindications
- Known hypersensitivity to the drug or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- During lactation
Side Effects
- Nausea
- Vomiting
- Epigastric pain
- Headache
- Irritability
- Insomnia
- Tachycardia
- Extrasystoles
- Tachypnea
- Hyperglycemia
- Albuminuria
- Severe cardiac arrhythmias
- Tonic-clonic seizure
Pregnancy & Lactation
- Evaluation of use during pregnancy case by case
- Contraindicated during lactation
- Animal tests showing no interference with pre and postnatal growth
Precautions & Warnings
- Factors reducing hepatic clearance of xanthine derivatives
- Monitoring of blood levels recommended
- Caution in patients with various conditions
Overdose Effects
- Severe cardiac arrhythmias
- Tonic-clonic seizure
- Intoxication signs
- No specific antidote
Therapeutic Class
- Bronchodilator
- Methyl xanthine derivatives
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
- To be used only on prescription of specialist physician