Imigra 5 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Flunarizine |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
- Prophylaxis of classic migraine
- Prophylaxis of common migraine
- Symptomatic treatment of vestibular vertigo
- Symptomatic treatment of peripheral vascular disease
- Symptomatic treatment of motion sickness
- Symptomatic treatment of refractory epilepsy
Pharmacology
Flunarizine is the difluorinated derivative of cinnarizine. It is a selective calcium channel antagonist. It prevents cellular calcium overload and has antihistaminic and sedative properties.
Dosage & Administration
- Starting dose for migraine prophylaxis: 10 mg at night for patients less than 65 years of age, 5 mg daily for patients older than 65 years
- Maintenance treatment for migraine prophylaxis
- Peripheral vascular disease dosage: 10 mg twice daily, up to 30 mg per day if required
- Vertigo & motion sickness dosage: 10-20 mg daily for adults, 5 mg daily for children (>40 kg)
- Epileptic seizure dosage: 15-20 mg daily in adults, 5 to 10 mg daily for children as add-on therapy
Interaction
Galactorrhoea reported in women on oral contraceptives within first two months of treatment. Hepatic enzyme inducers may require an increase in dosage.
Contraindications
Hypersensitivity to Flunarizine. Contra-indicated in patients with a history of depressive illness or pre-existing symptoms of Parkinson's disease or other extrapyramidal disorders.
Side Effects
- Drowsiness and/or fatigue
- Weight gain and/or increased appetite
- Depression
- Extrapyramidal symptoms
- Heartburn
- Nausea
- Insomnia
- Anxiety
- Galactorrhoea
- Dry mouth
- Muscle ache
- Skin rash
Pregnancy & Lactation
Safety not established
Precautions & Warnings
May lead to drowsiness, caution against driving or performing hazardous tasks, not suited for aborting a migraine attack, may give rise to extrapyramidal and depressive symptoms
Therapeutic Class
Miscellaneous prophylactic migraine preparations
Storage Conditions
Keep below 30°C, away from light and moisture, out of the reach of children