Cavapro 150 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Irbesartan |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of essential hypertension
- Treatment of renal disease in patients with hypertension and type 2 diabetes mellitus
Pharmacology
- Angiotensin II receptor antagonist
- Blocks vasoconstricting and aldosterone-secreting effects
Dosage & Administration
- Usual recommended initial and maintenance dose of 150 mg once daily
- Can be taken with or without food
- Consider initiation at 75 mg in haemodialysed patients and elderly over 75 years
- Dose adjustment not usually necessary for the elderly
- Not recommended for use in children and adolescents
Interaction
- Caution with diuretics and other antihypertensive agents
- Avoid concomitant use with potassium supplements and potassium-sparing diuretics
- Careful monitoring of serum lithium levels if coadministered with lithium
- Attenuation of antihypertensive effect with non-steroidal anti-inflammatory drugs
Contraindications
- Concomitant use with aliskiren in patients with diabetes and renal impairment
- Pregnancy
Side Effects
- Diarrhoea
- Fatigue
- Dyspepsia or heartburn
- Dizziness
- Orthostatic hypotension
- Nausea
- Vomiting
- Musculoskeletal pain
- Thrombocytopaenia
- Hyperkalaemia
- Elevated serum creatinine
Pregnancy & Lactation
- Contraindicated in the second and third trimesters of pregnancy
- Precautionary measure in the first trimester of pregnancy
- Contraindicated during lactation
- Not recommended due to insufficient safety data in children and adolescents
Precautions & Warnings
- Considerations for patients with specific cardiac conditions, renal impairment, and hepatic impairment
- Close monitoring of serum potassium levels for patients at risk of hyperkalaemia
- Special caution for patients with aortic or mitral stenosis, or obstructive hypertrophic cardiomyopathy
- Not recommended for patients with primary aldosteronism
- Caution in patients whose vascular tone and renal function depend on the renin-angiotensin-aldosterone system
- Potential risk of acute hypotension, azotaemia, oliguria, or acute renal failure
- Risk of excessive blood pressure decrease in certain patient populations
Use in Special Populations
- No dosage adjustment necessary for patients with impaired renal function
- Consider lower starting dose for haemodialysis patients
- No dosage adjustment necessary for patients with mild to moderate hepatic impairment
- Effects on renal and cardiovascular events not uniform across all subgroups
- Close monitoring of serum potassium for patients at risk of hyperkalaemia
- Special caution for patients with specific cardiac conditions
- Not recommended for patients with primary aldosteronism
- Potential risk of acute hypotension, azotaemia, oliguria, or acute renal failure
Overdose Effects
- Expected manifestations include hypotension and tachycardia
- No specific information available on treatment
- Symptomatic and supportive treatment recommended
- Suggested measures include induction of emesis and/or gastric lavage
Therapeutic Class
- Angiotensin II receptor blocker
Storage Conditions
- Store in a cool and dry place
- Protected from light