Pires-M (100 mg+1.1 mg+14 mg)/5 ml (Syrup)

Indications

• Relief of cough
• Relief of congestive symptoms
• Aiding restful sleep

Composition

• Gualfonosln BP: 100 mg
• Levomenthol BP: 1.1 mg
• Diphenhydramine Hydrochlorldo BP: 14 mg

Pharmacology

Guaifenesin reduces the viscosity of sputum, Levomenthol has local anesthetic and decongestant properties, Diphenhydramine Hydrochloride possesses antitussive, antihistaminic, and anticholinergic properties

Dosage & Administration

• For adults and children over 12 years: 2 teaspoonfuls syrup 4 times a day or as directed by the physician, maximum 8 teaspoonfuls syrup in 24 hours
• Use in Children & Adolescents: Efficacy and safety not established

Interaction

May potentiate effects of alcohol and CNS depressants, may potentiate effects of anticholinergics

Contraindications

Hypersensitivity to the product or any of its components, recent treatment with MAOIs

Side Effects

• Drowsiness
• Dizziness
• Nausea and vomiting
• Gastro-intestinal disturbance
• Dry mouth, nose and throat
• Difficulty in urination
• Blurred vision

Pregnancy & Lactation

Care should be taken during pregnancy, not associated with adverse effects in human fetus or infant

Precautions & Warnings

• May cause drowsiness
• Should not be taken by individuals with narrow-angle glaucoma or symptomatic prostatic hypertrophy
• Not for persistent or chronic cough without physician's direction

Overdose Effects

Guaifenesin may cause renal calculi when taken in excess

Therapeutic Class

Combined cough expectorants

Storage Conditions

Store at temperature not exceeding 30°C, protect from light & moisture, keep out of reach of children

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