Cavapro 300 mg (Tablet)
Unit Price: ৳ 24.00 (1 x 10: ৳ 240.00)
Strip Price: ৳ 240.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Irbesartan |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Title
- Irbesartan Tablet
Category
- Medicine
- Hypertension Medication
- Antihypertensive Drug
Description
- Treatment of essential hypertension
- Treatment of renal disease in patients with hypertension and type 2 diabetes mellitus
- Angiotensin II receptor antagonist
- Pharmacological effects on vasoconstriction and aldosterone secretion
- Dosage recommendations for adults, elderly, pediatric patients
- Interactions with diuretics, potassium supplements, lithium, NSAIDs
- Contraindications with aliskiren, pregnancy
- Possible side effects like diarrhea, fatigue, dizziness, hyperkalemia
- Guidelines for use in pregnancy and lactation
- Precautions for patients with renal artery stenosis, renal impairment, aortic or mitral stenosis, obstructive hypertrophic cardiomyopathy, and lactation
- Special considerations for patients with renal impairment, hepatic impairment, and primary aldosteronism
- Information on overdose effects and storage conditions
Dimensions
Color Options
Functions
- Treatment of hypertension
- Renal disease management
Materials
Technical Specifications
Design Elements
Usability Features
Dosage Recommendations
- Initial and maintenance dose of Irbesartan 150 mg once daily for adults
- Consideration of a lower starting dose for elderly and pediatric patients
- Titration up to Irbesartan 300 mg once daily for hypertensive type 2 diabetic patients
Interactions
- Effect of prior treatment with high dose diuretics on initiating therapy with Irbesartan
- Concomitant use of potassium-sparing diuretics, potassium supplements, and drugs that may increase serum potassium levels
- Possible reversible increases in serum lithium concentrations and toxicity with concomitant administration of lithium
- Attenuation of the antihypertensive effect when administered simultaneously with non-steroidal anti-inflammatory drugs
- Pharmacokinetic interactions with hydrochlorothiazide, warfarin, rifampicin, and digoxin
Contraindications
- Concomitant use with aliskiren in patients with diabetes and renal impairment (GFR <60 ml/min)
- Pregnancy
Possible Side Effects
- Diarrhoea
- Fatigue
- Dizziness
- Hyperkalaemia
- Elevated serum creatinine
- Orthostatic hypotension
- Nausea
- Vomiting
- Musculoskeletal pain
- Thrombocytopaenia
Guidelines for Pregnancy & Lactation
- Contraindicated in the second and third trimesters of pregnancy
- Precautionary measures during the first trimester of pregnancy
- Contraindicated during lactation
Precautions and Warnings
- Considerations for patients with unilateral or bilateral renal artery stenosis, intravascular volume depletion, aortic or mitral stenosis, or obstructive hypertrophic cardiomyopathy
- Special population considerations for renal impairment, hepatic impairment, hypertensive patients with type 2 diabetes and renal disease, hyperkalaemia, aortic and mitral valve stenosis, obstructive hypertrophic cardiomyopathy, primary aldosteronism
- General precautions for patients dependent on the renin-angiotensin-aldosterone system
Special Population Uses
- No dosage adjustment necessary in patients with impaired renal function
- Consideration of a lower starting dose for patients undergoing haemodialysis
- Consideration of a lower starting dose for patients with mild to moderate hepatic impairment
- Effects of Irbesartan on renal and cardiovascular events in hypertensive patients with type 2 diabetes and renal disease
- Risk of hyperkalaemia in the presence of renal impairment, overt proteinuria due to diabetic renal disease, and/or heart failure in patients at risk
Dosage Overdose Effects
- Experience with exposure to doses of up to 900 mg/day for 8 weeks revealed no toxicity
- Expected manifestations of overdosage include hypotension, tachycardia, and bradycardia
- No specific information available on the treatment of overdosage with Irbesartan
Therapeutic Class
- Angiotensin-ll receptor blocker
Storage Conditions
- Store in a cool and dry place
- Protected from light