Rivo 1 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Orion pharma ltd |
| Also available as |
Title and Categories
- Rivo 1 mg Tablet
- Medicine
- Pharmaceutical
Indications
- Treatment of panic disorder with or without agoraphobia
- Adjunct in the treatment of Lennox-Gastaut Syndrome
- Treatment of akinetic and myoclonic seizures
- Treatment of absence seizures
Pharmacology
- Exhibits anticonvulsive, sedative, muscle relaxing and anxiolytic effects
- Enhances GABAergic neurotransmission at inhibitory synapses
- Suppresses various types of paroxysmal activity including spike and wave discharge in absences seizures
Dosage & Administration
- Initial dose for adults with seizure disorders should not exceed 1.5 mg/day divided into three doses
- Initial dose for adults with panic disorder is 0.25 mg
- Pediatric patients' initial dose should be between 0.01 and 0.03 mg/kg/day
Interaction
- Does not alter the pharmacokinetics of phenytoin, carbamazepine or phenobarbital
Contraindications
- Hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Contradicted in acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Tremor
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential for producing congenital malformations
- Should only be administered to pregnant women if benefits outweigh the risk to the fetus
- Active ingredient found to pass into maternal milk in small amounts
- Breastfeeding should be discontinued if compelling indication for use
Precautions & Warnings
- May increase the incidence or precipitate the onset of generalized tonic-clonic seizures
- Concomitant use with valproic acid may produce absence status
- Increased production of saliva and bronchial secretion in infants and small children
- Benzodiazepine pharmacologic effects appear to be greater in elderly patients
Use in Special Populations
- Pediatric use may cause increased production of saliva and bronchial secretion
- Benzodiazepine effects appear greater in elderly patients
- Renal impairment does not affect pharmacokinetics
- Hepatic impairment may affect plasma protein binding
Overdose Effects
- Common symptoms include drowsiness, ataxia, dysarthria, and nystagmus
- May lead to areflexia, apnea, hypotension, and coma
- Increased frequency of seizures may occur
- Respiratory depressant effects more serious in patients with respiratory disease
- Benzodiazepines increase the effects of other CNS depressants
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Contents of the vial must be diluted with 1 ml of water for injection
- IV injection should be administered slowly with continuous monitoring of EEG, respiration, and blood pressure
- Rivo can be diluted for infusion in various diluting media
- IM route should be used only in exceptional cases
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
Common Questions
- Rivo 1 mg Tablet is not a sleeping pill
- Take Rivo 1 mg Tablet as long as advised by the doctor
- Common withdrawal symptoms include difficulty in sleeping and changes in mood
- Pay attention to changes in mood, behaviors, thoughts, or feelings for early symptoms of suicidal thoughts and actions
- Rivo 1 mg Tablet may cause weight gain and weight loss
- Rivo 1 mg Tablet does not affect memory