Ceftriaid 500 mg/vial (IV Injection)

500 mg vial: ৳ 200.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Labaid pharma ltd
Also available as
Ceftriaid 500 mg injection Ceftriaid 1 gm injection Ceftriaid 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Mode of Action

Bactericidal activity against Gram-positive and Gram-negative organisms by interfering with bacterial cell wall synthesis

Dosage

  • Adult:
    • 1 to 2 gm by intravenous or intramuscular administration once a day
    • Maximum dose: 4 gm/day
  • Infants and Children (01 month or older):
    • 50 to 75 mg/kg intravenous or intramuscular administration once a day
    • Maximum dose: 2 gm/day
  • Duration of therapy: Usual duration is 4 to 14 days; longer therapy may be required for complicated infections

Administration

  • Preparation of solutions for intramuscular/intravenous injections
  • Administered over 2-4 minutes by intramuscular or intravenous injection or by tubing infusion over a period of 30 minutes
  • Patient tolerance test recommended before treatment

Interaction

No drug interactions reported

Contraindications

Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects including diarrhea, nausea, vomiting, stomatitis, and glossitis
  • Cutaneous reactions including rash, pruritus, urticaria, edema, and erythema multiforme
  • Hematologic reactions including eosinophilia, thrombocytopenia, leucopenia, anemia, and neutropenia
  • Hepatic reactions including elevations of SGOT or SGPT, bilirubinemia
  • CNS reactions including nervousness, confusion, sleep disturbances, headache, hyperactivity, convulsion, hypertonia, and dizziness
  • Local phlebitis occurs rarely following intravenous administration

Pregnancy & Lactation

Safety in human pregnancy not established; caution in lactating mothers

Precautions & Warnings

  • Anaphylactic shock
  • Sonographic shadows suggesting sludge in the gallbladder
  • Regular blood picture checks during prolonged treatment

Use in Special Populations

Not to be given to premature and newborn neonates (up to 28 days of age)

Overdose Effects

No specific antidote; treatment should be symptomatic

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30° C), away from light & moisture; Keep out of the reach of children

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