Eprazol 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 10.03 (5 x 6: ৳ 300.90)
Strip Price: ৳ 60.18

Medicine Details

Category Details
Generic Esomeprazole
Company Labaid pharma ltd
Also available as
Eprazol 20 mg capsule

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of acid-related Dyspepsia
  • Treatment of Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Enteric-coated pellet formulation
  • Peak plasma levels occur at approximately 1.5 hours
  • 97% bound to plasma proteins

Dosage

  • 20 mg or 40 mg Once Daily for 4-8 Weeks for Erosive Esophagitis
  • 20 mg Once Daily for maintenance of healing of erosive esophagitis
  • 20 mg Once Daily for symptomatic GERD
  • Triple Therapy for Helicobacter Pylori eradication
  • 20-80 mg Once Daily for Zollinger-Ellison Syndrome
  • 20-40 mg Once Daily for Acid-related Dyspepsia
  • 20 mg Once Daily for Duodenal ulcer
  • 20-40 mg Once Daily for Gastric ulcer
  • IV Injection or IV infusion for various conditions based on patient's age and weight

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension should be taken with water and consumed within 30 minutes
  • IV Injection should be administrated intravenously over a period of at least 3 minutes

Interaction

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • No clinically relevant interactions with specific CYP enzymes expected
  • Potential interference with the absorption of certain drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • No studies on excretion of esomeprazole in milk

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Patients with difficulty swallowing capsules can mix the pellets with applesauce

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy observed between the elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency

Overdose Effects

  • Signs of acute toxicity include reduced motor activity and tremors
  • No specific antidote known

Storage Conditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure available

Common Questions about Eprazol 40 mg Capsule

  • Used to treat gastroesophageal reflux disease (GERD), ulcers, and other conditions related to excessive stomach acid
  • Common side effects include headache, diarrhea, nausea, and constipation
  • Pregnant or breastfeeding women should discuss the risks and benefits with a doctor
  • Usually starts to work within a few hours of consumption

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