Maxbac 250 mg/vial (IM/IV Injection)

250 mg vial: ৳ 85.26

Medicine Details

Category Details
Generic Ceftazidime pentahydrate
Company Rangs pharmaceuticals ltd
Also available as
Maxbac 500 mg injection Maxbac 1 gm injection

Title

  • Maxbac Injection

Categories

  • Antibiotic
  • Medication
  • Pharmaceutical

Description

Maxbac Injection is indicated for the treatment of lower respiratory tract infections, skin and skin structure infections, urinary tract infections, bacterial septicemia, bone and joint infections, gynecologic infections, intraabdominal infections, and central nervous system infections caused by susceptible strains of designated organisms. It is a broad-spectrum, beta-lactam antibiotic for parenteral administration.

Dosage

Usual adult dosage is 1 gram administered intravenously or intramuscularly every 8 to 12 hours. Dosage may vary based on the severity of infection, susceptibility of causative organisms, and patient's renal function.

Administration

Ceftazidime may be given intravenously or by deep IM injection into a large muscle mass such as the upper outer quadrant of the gluteus maximus or lateral part of the thigh. Intra-arterial administration should be avoided.

Contraindications

Ceftazidime is contraindicated in patients with known hypersensitivity to cephalosporins.

Side Effects

  • Local reactions following IV injection
  • Allergic reactions
  • Gastrointestinal symptoms
  • Central nervous system reactions

Pregnancy & Lactation

Use during pregnancy only if clearly needed. Caution is advised in nursing mothers.

Precautions & Warnings

  • Dosage reduction in renal insufficiency
  • Prescribed with caution in individuals with a history of gastrointestinal disease

Therapeutic Class

Third generation Cephalosporins

Reconstitution

Single-dose vial Administration Amount of WFI to be added: 250 mg IM in 1.5 ml, 250 mg IV in 5 ml, 500 mg IM in 1.5 ml, 500 mg IV in 5 ml, 1 g IM in 3 ml, 1 g IV in 10 ml.

Storage Conditions

Store below 25°C, protected from light and moisture. Reconstituted solutions are stable for up to 24 h if stored between 2°C - 8°C.

Indications

  • Lower Respiratory Tract Infections
  • Skin and Skin Structure Infections
  • Urinary Tract Infections
  • Bacterial Septicemia
  • Bone and Joint Infections
  • Gynecologic Infections
  • Intraabdominal Infections
  • Central Nervous System Infections

Pharmacology

Ceftazidime is a broad-spectrum, beta-lactam antibiotic that exerts its effect by inhibition of enzymes responsible for cell-wall synthesis. It is highly stable to most clinically important beta-lactamases, both plasmid or chromosomal.

Use in Special Populations

  • Impaired Renal Function
  • Impaired Hepatic Function

Overdose Effects

Reactions may include seizure activity, encephalopathy, asterixis, neuromuscular excitability, and coma. Supportive treatment should be given to patients who receive an acute overdosage.

Pediatric Uses

The dosage in pediatric patients varies based on age and weight, with specific considerations for neonates and children up to 2 months of age.

Reconstitution Information

Single-dose vial Administration Amount of WFI to be added: 250 mg IM in 1.5 ml, 250 mg IV in 5 ml, 500 mg IM in 1.5 ml, 500 mg IV in 5 ml, 1 g IM in 3 ml, 1 g IV in 10 ml.

Drug Classes

  • Cephalosporin Antibiotics

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