Linalit-M 2.5 mg+500 mg (Tablet)

Unit Price: ৳ 12.00 (30's pack: ৳ 360.00)

Medicine Details

Category Details
Generic Linagliptin metformin hydrochloride
Company The white horse pharmaceuticals ltd
Also available as
Linalit m 25 mg tablet

Indications

  • Adjunct to diet and exercise
  • Improves glycemic control
  • Adults with type 2 diabetes mellitus

Pharmacology

  • Inhibitor of DPP-4 enzyme
  • Increases active incretin hormones
  • Stimulates insulin release
  • Decreases glucagon secretion
  • Biguanide type oral antihyperglycemic drug
  • Lowers plasma glucose
  • Decreases hepatic glucose production
  • Improves insulin sensitivity

Dosage & Administration

  • Individualized dosage
  • Maximum recommended dose
  • Dose escalation
  • Different starting doses
  • Immediate release and extended release tablets
  • Twice daily and once daily administration

Interaction

  • Cationic drugs interaction
  • Carbonic anhydrase inhibitors interaction
  • Inducers of P-glycoprotein and CYP3A4 enzymes interaction
  • Drugs affecting glycemic control interaction

Contraindications

  • Renal impairment contraindication
  • Acute or chronic metabolic acidosis contraindication
  • Hypersensitivity contraindication

Side Effects

  • Nasopharyngitis
  • Diarrhea
  • Hypoglycemia

Pregnancy & Lactation

  • Use during pregnancy if clearly needed
  • Caution during lactation

Precautions & Warnings

  • Discontinue in lactic acidosis
  • Discontinue in suspected pancreatitis
  • Discontinue temporarily in certain medical procedures
  • Monitoring of hematologic parameters
  • Symptoms and precautions for lactic acidosis
  • Hypoglycemia precautions
  • Alcohol and other medicines precautions
  • Counseling and travel precautions
  • Emergency preparation precautions

Overdose Effects

  • Supportive measures for overdose
  • Hemodialysis or peritoneal dialysis for Metformin Hydrochloride
  • No dose-related clinical adverse drug reactions
  • Hypoglycemia and lactic acidosis in Metformin Hydrochloride overdose

Therapeutic Class

  • Combination oral hypoglycemic preparations

Storage Conditions

  • Cool & dry place
  • Protected from light & moisture
  • Keep out of the reach of children

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