Anin 50 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Losartan potassium |
| Company | Delta pharma ltd |
Indications
- Hypertension
- Renal Protection in Type-2 Diabetic Patients with Proteinuria
Pharmacology
- Non-peptide Orally Active Angiotensin II Receptor Blocker
- Binds to AT1 Receptor in Various Tissues
- Reduces Vasoconstriction and Aldosterone Release
Dosage & Administration
- Usual Starting and Maintenance Dose of 50 mg Once Daily
- 25 mg Twice Daily for Inadequate Effect
- Total Daily Dose Ranges from 25 mg to 100 mg
- Different Dosage for Patients upto 75 years and over 75 years
Interaction
- Rifampicin and Fluconazole reduce levels of active metabolite of Anin
- Concomitant use of Anin and Hydrochlorothiazide may potentiate antihypertensive effects
- Concomitant use of potassium-sparing diuretics, potassium supplements, or salt substitutes may increase serum potassium
- Attenuated antihypertensive effect by non-steroidal anti-inflammatory drug
Contraindications
- Contradicted in Pregnant Women and Hypersensitive Patients
- Not to be administered with Aliskiren in patients with diabetes
Side Effects
- Mild and Transient Side Effects
- Common side effects: dizziness, diarrhea, nasal congestion, cough, upper respiratory infection
- Other side effects: fatigue, edema, abdominal pain, chest pain, nausea, headache, pharyngitis
Pregnancy & Lactation
- Pregnancy Category D
- Risk increases if administered during second or third trimesters
- Unknown excretion in human milk
Precautions & Warnings
- Reduces fetal renal function and increases fetal and neonatal morbidity and death when used during the second and third trimesters of pregnancy
- Symptomatic hypotension may occur in intravascularly volume-depleted patients
- Significantly increased plasma concentration in cirrhotic patients
- Changes in renal function including renal failure in renal impaired patients
Use in Special Populations
- Different Dosage for patients with mild, moderate to severe renal impairment, or on dialysis
- Consider lower dose for patients with a history of hepatic impairment
Therapeutic Class
- Angiotensin-II Receptor Blocker
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children