Anreb 50 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Losartan potassium |
| Company | General pharmaceuticals ltd |
| Also available as |
Indications
- Hypertension treatment
- Renal disease delay in diabetics
Pharmacology
- First non-peptide orally active angiotensin II receptor blocker
- Reduces vasoconstriction and aldosterone release
Dosage & Administration
- Usual starting and maintenance dose of 50 mg once daily
- Total daily dose ranges from 25 mg to 100 mg
- Dosage adjustment for patients over 75 years
Interaction
- Reduction in active metabolite levels with Rifampicin and fluconazole
- Potentiation of antihypertensive effects with hydrochlorothiazide
- Increase in serum potassium with potassium-sparing diuretics or supplements
Contraindications
- Contraindicated in pregnant women
- Contraindicated in patients hypersensitive to any component
- Should not be administered with Aliskiren in diabetic patients
Side Effects
- Dizziness
- Diarrhea
- Nasal congestion
- Cough
- Fatigue
- Edema
- Abdominal pain
- Chest pain
- Nausea
- Headache
- Pharyngitis
Pregnancy & Lactation
- Pregnancy Category D
- Risk to the fetus increases if administered during second or third trimesters
Precautions & Warnings
- Reduces fetal renal function during second and third trimesters
- Symptomatic hypotension in intravascularly volume-depleted patients
- Significantly increased plasma concentration in cirrhotic patients
- Changes in renal function including renal failure reported in renal impaired patients
Use in Special Populations
- No initial dosage adjustment necessary in patients with mild renal impairment
- Lower starting dose recommended for patients with moderate to severe renal impairment or on dialysis
- Lower dose considered for patients with history of hepatic impairment
Therapeutic Class
- Angiotensin-II receptor blocker
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children