Calnor 5 mg+40 mg (Tablet)

Unit Price: ৳ 20.00 (3 x 14: ৳ 840.00)
Strip Price: ৳ 280.00

Medicine Details

Category Details
Generic Amlodipine besilate olmesartan medoxomil
Company Opsonin pharma ltd
Also available as
Calnor 5 mg tablet Calnor 10 mg tablet Calnor 10 mg tablet

Indications

  • Treatment of hypertension alone or with other antihypertensive agents
  • Lowering blood pressure
  • Initial therapy for patients likely to need multiple antihypertensive agents

Pharmacology

  • Amlodipine as a dihydropyridine calcium channel blocker
  • Greater effect on vascular smooth muscle cells than on cardiac muscle cells
  • Peripheral arterial vasodilator
  • Olmesartan Medoxomil as a selective blocker of AT1 receptor

Dosage & Administration

  • Start with 5/20 mg once daily for 1 to 2 weeks
  • Titrate up to a maximum of 10/40 mg once daily
  • Lower starting dose of Amlodipine for elderly patients (2.5 mg for patients 75 years)

Interaction

  • Potential attenuation by NSAIDs including selective COX-2 inhibitors
  • Close monitoring of blood pressure, renal function, and electrolytes

Contraindications

  • Not to be co-administered with Aliskiren in patients with diabetes

Side Effects

  • Peripheral edema
  • Headache
  • Flushing
  • Dizziness
  • Potential for sprue-like enteropathy

Pregnancy & Lactation

  • Pregnancy Category D
  • Avoid in 2nd and 3rd trimester
  • Potential adverse effects on the nursing infant

Precautions & Warnings

  • Risk for hypotension in volume- or salt-depleted patients
  • Vasodilation in patients with severe aortic stenosis
  • Increased frequency, duration, or severity of angina or acute MI in patients with severe obstructive coronary artery disease

Use in Special Populations

  • No established safety and effectiveness in pediatric patients
  • No overall differences in safety or effectiveness in subjects 65 years of age or older
  • No studies in patients with renal impairment
  • Initial therapy not recommended in hepatically impaired patients

Overdose Effects

  • No available information on human overdose

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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