Finix 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (9 x 10: ৳ 720.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Rabeprazole sodium
Company Opsonin pharma ltd
Also available as
Finix 20 mg tablet Finix 10 mg capsule

Indications

  • Active duodenal ulcer
  • Active benign gastric ulcer
  • Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • Zollinger-Ellison Syndrome
  • In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease.

Pharmacology

Rabeprazole suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell.

Dosage

  • 20 mg to be taken once daily in the morning for active duodenal ulcer and active benign gastric ulcer
  • 20 mg to be taken once daily for four to eight weeks for erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Maintenance dose of rabeprazole sodium 20 mg or 10 mg once daily for long-term management
  • 10 mg once daily for symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • 5 mg once daily for pediatric patients 1 to 11 years of age (Less than 15 kg)
  • 10 mg once daily for pediatric patients 1 to 11 years of age (15 kg or more)
  • 60 mg once a day for Zollinger-Ellison Syndrome
  • Eradication therapy: Rabeprazole sodium 20 mg twice daily, clarithromycin 500 mg twice daily, and amoxicillin 1g twice daily for 7 days.

Administration

Rabeprazole tablets should be taken in the morning, before eating, and swallowed whole.

Interaction

Co-administration with ketoconazole or itraconazole may result in a significant decrease in antifungal plasma levels; no interaction with liquid antacids observed; atazanavir absorption is pH-dependent.

Contraindications

Hypersensitivity to the active substance or to any of the excipients; contra-indicated in pregnancy and during breastfeeding.

Side Effects

  • Headache
  • Diarrhoea
  • Abdominal pain
  • Vomiting
  • Constipation
  • Dry mouth
  • Increased or decreased appetite
  • Muscle pain
  • Drowsiness
  • Dizziness

Pregnancy & Lactation

US FDA pregnancy category 'C'; likely excreted in human milk; a decision should be made whether to discontinue nursing or discontinue the drug.

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric or oesophageal malignancy
  • Regular surveillance for patients on long-term treatment
  • Modestly increased risk of hip, wrist, and spine fracture
  • Risk of cross-hypersensitivity reactions with other proton pump inhibitors
  • Potential of blood dyscrasias and hepatic enzyme abnormalities
  • Severe hypomagnesaemia reported in patients treated with PPIs
  • Reduction in absorption of vitamin B12
  • Association with subacute cutaneous lupus erythematosus (SCLE)
  • Interference with laboratory tests

Use in Special Populations

  • No dosage adjustment necessary for patients with renal or hepatic impairment
  • Not recommended for use in children

Overdose Effects

Maximum established exposure has not exceeded 60 mg twice daily or 160 mg once daily; effects are generally minimal, representative of the known adverse event profile and reversible without further medical intervention.

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Keep below 30°C temperature, away from light & moisture; keep out of the reach of children.

Chemical Structure

  • Molecular Formula: C18H21N3O3S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-942-rabeprazole-sodium-chemical-structure-atwg0Q4PlndQZhOY9GHX.svg

Common Questions about Finix 20 mg Capsule

  • Proton pump inhibitor (PPI) that suppresses gastric acid secretion
  • Used to treat duodenal ulcer, gastric ulcer, GERD, Zollinger-Ellison Syndrome, Helicobacter pylori eradication
  • Common side effects include diarrhea, constipation, nausea, vomiting, headache, dizziness, and dry mouth
  • Should be taken with food; length of treatment depends on the condition being treated

Quick Tips

  • Well-tolerated medicine providing long-term relief
  • Avoid eating late at night or before bedtime
  • Inform doctor about persistent symptoms
  • Long-term use may cause weak bones and a deficiency of minerals such as magnesium

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