Flucon 50 mg/5 ml (Powder for Suspension)
35 ml bottle: ৳ 78.52
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Inhibitor of fungal cytochrome P-450 dependent enzymes
- Responsible for the synthesis of ergosterol
Dosage & Administration
- Multiple dosage instructions for different indications
- Different dosages for adults and children
- Modification of dosage intervals for patients with renal impairment
- Renal clearance in children
Interaction
- Interaction with warfarin
- Interaction with oral sulphonyl ureas
- Interaction with hydrochlorothiazide
- Interaction with phenytoin
- Interaction with rifampicin
- Interaction with combined oral contraceptive
- Increased plasma concentrations of cyclosporin
- No clinically significant impairment of absorption with food, cemetidine, antacids or following total body irradiation
- Decrease in mean plasma clearance of theophyline
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rarely encountered rash and anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects seen in animals at high dose levels
- Little use during human pregnancy
- Not recommended in pregnancy or in women of child bearing potential
Precautions & Warnings
- Observed abnormalities in hepatic, renal, haematological and other biochemical function tests in some patients
- Rare occurrences of hepatic necrosis
- Development of severe cutaneous reactions in rare cases
- Not recommended during lactation
Use in Special Populations
- Normal dose usage in elderly if no evidence of renal impairment
- Dosage adjustments for patients with renal impairment
Overdose Effects
- Supportive measures and symptomatic treatment
- Potential use of gastric lavage
- Forced volume diuresis to increase elimination rate
- Approximately 50% decrease in plasma levels after haemodialysis
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children