Sitadus 50 mg (Tablet)

Unit Price: ৳ 15.05 (3 x 10: ৳ 451.50)
Strip Price: ৳ 150.50

Medicine Details

Indications

  • Adjunct to diet and exercise
  • Glycemic control
  • Type 2 diabetes mellitus

Pharmacology

  • DPP-4 inhibitor
  • Incretin hormones
  • Glucagon-like peptide-1 (GLP-1)
  • Insulinotropic polypeptide (GIP)
  • Blood glucose regulation

Dosage & Administration

  • Recommended dose: 50mg twice daily, 100mg once daily
  • Can be taken with or without food

Interaction

  • Effects on other drugs
  • Did not alter pharmacokinetics of certain drugs
  • Slight increase in Digoxin concentration

Contraindications

  • Serious hypersensitivity reaction to sitagliptin

Side Effects

  • Headache
  • Upper respiratory tract infection
  • Nasopharyngitis
  • Hypoglycemia

Pregnancy & Lactation

  • Pregnancy Category B
  • Secreted in lactating rat's milk
  • Caution in nursing women

Precautions & Warnings

  • Discontinue if pancreatitis suspected
  • Dosage adjustment in renal insufficiency
  • Use with medications known to cause Hypoglycemia
  • Hypersensitivity Reactions

Use in Special Populations

  • Pediatric use not established
  • Dose adjustment in elderly with decreased renal function
  • Different doses for mild, moderate, and severe renal insufficiency
  • Elderly patients with decreased renal function

Overdose Effects

  • Maximal mean increases in QTc
  • No dose-related clinical adverse reactions observed with doses up to 600mg per day
  • Modestly dialyzable

Therapeutic Class

  • Dipeptidyl Peptidase-4 (DPP-4) inhibitor

Storage Conditions

  • Store below 25°C
  • In a dry place away from light
  • Out of reach of children
  • Do not use later than the date of expiry
  • Dispensed only on prescription

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