Torcin D 0.1%+0.3% (Ophthalmic Solution)

5 ml drop: ৳ 150.00

Medicine Details

Category Details
Generic Dexamethasone tobramycin
Company Opsonin pharma ltd
Also available as
Torcin d 01 03 eye ointment

Indications

  • Steroid responsive inflammatory ocular conditions
  • Chronic anterior uveitis
  • Corneal injury from chemical radiation or thermal burns
  • Penetration of foreign bodies

Pharmacology

  • Bactericidal activity of Tobramycin
  • Inhibition of normal protein synthesis in susceptible bacteria
  • Action on ribosome causing bacterial misreading of messenger RNA
  • Inhibition of phospholipase A2 by Dexamethasone
  • Inhibition of chemo-tactic infiltration of neutrophils into the site of inflammation

Dosage & Administration

  • Eye Drops: 3-5 times per day into the conjunctival sac
  • Increased dosage during the initial 24 to 48 hours
  • Eye Ointment: 3-4 times per day into the conjunctival sac
  • Pediatric Use: Safety and effectiveness not established below the age of 2 years

Interaction

  • No specific interaction studies performed with Torcin D eye drops
  • Interval of 10 minutes between successive applications for concomitant therapy

Contraindications

  • Epithelial herpes simplex keratitis
  • Vaccinia and varicella
  • Mycobacterial infection of the eye
  • Hypersensitivity to any component of the medication

Side Effects

  • Hypersensitivity and localized ocular toxicity
  • Lid itching, swelling and conjunctival erythema
  • Elevation of intraocular pressure with possible development of glaucoma
  • Optic nerve damage
  • Posterior subcapsular cataract formation
  • Delayed wound healing

Pregnancy & Lactation

  • Use during pregnancy if potential benefit justifies the potent risk to the fetus
  • Caution during nursing as systemic absorption to produce detectable quantities in human milk is unknown

Precautions & Warnings

  • Consideration of fungal infections of the cornea after long-term steroid dosing
  • Prolonged use may result in overgrowth of non-susceptible organisms
  • Risk of cross-sensitivity to other aminoglycoside antibiotics

Overdose Effects

  • No known overdose through local administration
  • Specific measures to reduce resorption in case of accidental oral intake
  • No specific antidote

Therapeutic Class

Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

Store at room temperature. Close the bottle immediately after use. Do not use for longer than one month after opening the bottle.

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