Trimazole 1% (Topical Solution)

20 ml bottle: ৳ 68.00

Medicine Details

Category Details
Generic Clotrimazole topical
Company Opsonin pharma ltd
Also available as

Indications

  • Treatment of dermatomycoses due to dermatophytes
  • Treatment of dermatomycoses due to yeasts
  • Treatment of dermatomycoses due to moulds and other fungi
  • Treatment of skin diseases showing superinfections with these fungi
  • Treatment of interdigital mycoses (e.g. athlete's foot)
  • Treatment of paronychias associated with nail mycoses
  • Treatment of mycoses in skin folds
  • Treatment of Candida vulvitis
  • Treatment of Candida balanitis
  • Treatment of Pityriasis versicolor
  • Treatment of erythrasma

Description

  • Broad-spectrum antifungal agent
  • Treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, moulds, and bacteroids
  • Active against gram-positive bacteria especially Staphylococci and Tricomonas
  • Alters the permeability of fungal cell walls
  • Inhibition of ergosterol synthesis
  • Acts by damaging the permeability barrier in the cell membrane of fungi

Pharmacology

  • Damages the permeability barrier in the cell membrane of fungi
  • Causes inhibition of ergosterol biosynthesis
  • Inhibition of lanosterol 14-demethylase (CYP51)
  • Blocks calcium-dependent potassium channels and voltage-dependent calcium channels

Dosage & Administration

  • Thinly applied 2-3 times daily to the infected sites and rubbed in
  • Recommended duration of treatment for various conditions
  • Application to affected areas and rub in gently two or three times daily
  • Odorless and can be washed off without staining clothing

Interaction

  • No information available

Contraindications

  • Hypersensitivity to Clotrimazole

Side Effects

  • Well tolerated when applied topically
  • Local irritation or burning sensation may occur in a few cases

Pregnancy & Lactation

  • Recommended to be used in pregnancy only when considered necessary by the physician

Therapeutic Class

  • Drugs for subcutaneous and mycoses
  • Topical Antifungal preparations

Storage Conditions

  • Keep below 25°C temperature
  • Keep away from light and moisture
  • Keep out of the reach of children

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