Murein 500 mg (Capsule)

Unit Price: ৳ 10.50 (7 x 4: ৳ 294.00)
Strip Price: ৳ 42.00

Medicine Details

Category Details
Generic Flucloxacillin sodium
Company One pharma ltd

Title

  • Murein

Categories

  • Medicine
  • Antibiotic

Description

  • Murein is indicated for the treatment of infections due to Gram-positive organisms, including infections caused by penicillinase producing staphylococci.

Indications

  • Treatment of skin and soft tissue infections
  • Treatment of respiratory tract infections
  • Treatment of osteomyelitis
  • Treatment of enteritis
  • Prophylactic use during major surgical procedures

Pharmacology

  • Inhibition of cell wall formation in bacteria
  • Bactericidal effect against penicillinase-producing staphylococci

Dosage

  • Adult oral dose: 250 mg four times daily
  • Severe infections may require doubled dosage
  • Children dosage: 1/2 of adult dose for 2-10 years, 1/4 for under 2 years

Administration

  • Oral doses should be administered 1 hour before meal

Interaction

  • Concurrent use may increase Murein levels in blood

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Gastrointestinal side effects: nausea, vomiting, diarrhea, dyspepsia
  • Rashes, urticaria, purpura, fever
  • Other reported side effects: interstitial nephritis, hepatitis, cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Caution in use during pregnancy and lactation

Precautions & Warnings

  • Caution in patients with hepatic dysfunction
  • Caution in patients with allergic diathesis

Use in Special Populations

  • Reduced dose in severe renal failure (creatinine clearance <10 ml/min)

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Administered via intraarticular injection
  • Administered via intrapleural injection
  • Administered via nebulizer inhalation

Storage Conditions

  • Keep in a dry place away from light and heat

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