Cardon 50 mg (Tablet)
Unit Price: ৳ 10.00 (4 x 10: ৳ 400.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Losartan potassium |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Hypertension
- Renal Protection in Type-2 Diabetic Patients with Proteinuria
Pharmacology
- Non-peptide orally active angiotensin II receptor blocker
- Binds to AT1 receptor in various tissues
- Reduces vasoconstriction and aldosterone release
Dosage & Administration
- Usual starting dose of 50 mg once daily
- Maximum total daily dose of 100 mg
- Adjustments for intravascular volume-depletion and age
Interaction
- Reduction of active metabolite levels by Rifampicin and fluconazole
- Potentiation of antihypertensive effects with hydrochlorothiazide
- Possible increase in serum potassium with potassium-sparing diuretics
- Attenuation of antihypertensive effect by indomethacin
Contraindications
- Pregnancy
- Hypersensitivity to any component
- Concomitant use with Aliskiren in patients with diabetes
Side Effects
- Mild and transient side effects
- Common side effects: dizziness, diarrhea, nasal congestion, cough, upper respiratory infection
- Other side effects: fatigue, oedema, abdominal pain, chest pain, nausea, headache, pharyngitis
Pregnancy & Lactation
- Pregnancy Category D
- Potential excretion in human milk
- Consideration of adverse effects on the nursing infant
Precautions & Warnings
- Reduced fetal renal function and increased morbidity and death in second and third trimesters
- Symptomatic hypotension in intravascularly volume-depleted patients
- Significantly increased plasma concentration in cirrhotic patients
- Changes in renal function and failure in renal-impaired patients
Use in Special Populations
- Dosage adjustments in mild, moderate, or severe renal impairment
- Consideration of hepatic impairment
- Administration with other antihypertensive agents
- Contraindications and warnings related to pregnancy, hypersensitivity, renal artery stenosis, and potassium-sparing diuretics
Therapeutic Class
- Angiotensin-II receptor blocker
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children