Pileus 150 mg (Capsule)
Unit Price: ৳ 22.00 (1 x 10: ৳ 220.00)
Strip Price: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | One pharma ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Inhibitor of fungal cytochrome P-450 dependent enzymes
Dosage & Administration
- Single doses for various infections
- Weekly doses for specific conditions
- Dosage in children based on weight
- Dosage adjustment for elderly and patients with renal impairment
Interaction
- Potential interactions with drugs like warfarin, sulphonyl ureas, hydrochlorothiazide, phenytoin, rifampicin
- No significant impairment of absorption with food, cimetidine, antacids
Contraindications
- Hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Well tolerated in general
- Common gastrointestinal side effects
- Rarely encountered adverse events
Pregnancy & Lactation
- Adverse fetal effects observed in animals at high doses
- Not recommended during pregnancy or in women of childbearing potential without adequate contraception
Precautions & Warnings
- Abnormalities in hepatic, renal, and biochemical function tests observed in some patients
- Rare cases of severe cutaneous reactions reported
- Consideration of risk-benefit ratio in patients with liver enzyme rise
- Discontinue therapy if rash develops
- Not recommended during lactation
Use in Special Populations
- Normal dose for elderly if no evidence of renal impairment
- Dosage adjustments in patients with renal impairment based on creatinine clearance
Overdose Effects
- Supportive measures and symptomatic treatment in overdosage
- Possibility of increased elimination rate with forced volume diuresis
- Approximately 50% decrease in plasma levels with haemodialysis
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Keep in dry place away from light and heat
- Keep out of the reach of children