ESO 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Esomeprazole
Company Asiatic laboratories ltd
Also available as

Title

  • ESO 40 mg Tablet

Categories

  • Medication
  • Pharmaceutical

Description

  • Oral capsule for the treatment of heartburn, GERD, erosive esophagitis, H. pylori infection, Zollinger-Ellison Syndrome, Dyspepsia, Duodenal & Gastric ulcers

Indications

  • Relieves chronic heartburn symptoms
  • Heals erosive esophagitis
  • Maintains healing of erosive esophagitis
  • Eradicates Helicobacter pylori infection
  • Treats Zollinger-Ellison Syndrome
  • Manages Acid related Dyspepsia
  • Heals Duodenal & Gastric ulcers

Pharmacology

  • Supresses gastric acid secretion
  • Proton pump inhibitor
  • Enters systemic circulation within 1.5 hours after administration
  • Metabolized in the liver
  • Extensively bound to plasma proteins
  • Excreted as inactive metabolites in the urine and feces

Dosage

  • 20 mg or 40 mg once daily for 4-8 weeks for healing erosive esophagitis
  • 20 mg once daily for maintenance of healing of erosive esophagitis
  • 20 mg once daily for symptomatic GERD
  • Esomeprazole 40 mg Once Daily for 10 days in combination therapy for H.pylori eradication
  • 20-80 mg once daily for Zollinger-Ellison Syndrome
  • 20-40 mg once daily for acid-related Dyspepsia
  • 20 mg once daily for 2-4 weeks for Duodenal ulcer, 20-40 mg once daily for 4-8 weeks for Gastric ulcer
  • Dosage adjustments for pediatric and adult patients based on body weight
  • 80 mg for adults for risk reduction of rebleeding of Gastric or Duodenal Ulcers following therapeutic endoscopy

Administration

  • Oral capsule should be swallowed whole and taken 1 hour before meals
  • Oral suspension should be taken with water and stirred well
  • IV injection or infusion for specific conditions and patient demographics

Interaction

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • No clinically relevant interactions with certain drugs metabolized by specific CYP enzymes
  • Potential interference with absorption of drugs affected by gastric pH
  • No significant interactions with specific drugs like phenytoin, warfarin, clarithromycin or amoxicillin

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side effects

  • Frequently occurring adverse events include headache, diarrhea, nausea, flatulence, abdominal pain, constipation and dry mouth

Pregnancy and lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Excretion in milk not studied
  • Breast-feeding should be discontinued if use is considered essential

Precautions and warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Specific instructions for patients regarding capsule administration and use of antacids
  • Paediatric and geriatric use, hepatic and renal insufficiency considerations

Overdose effects

  • Lethal to rats at high doses
  • Specific signs of acute toxicity in animals
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage conditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical structure

  • Molecular formula: C17H19N3O3S
  • Chemical structure available in image format

Commonly asked questions

  • What is ESO 40 mg Tablet?
  • What is ESO 40 mg Tablet used for?
  • What are the side effects of ESO 40 mg Tablet?
  • Can I take ESO 40 mg Tablet if I am pregnant or breastfeeding?
  • Quick tips for using ESO 40 mg Tablet

Other information

  • Additional information on pharmacokinetics, combination therapy, and specific patient demographics

Dosage forms

  • Oral capsules
  • Oral suspension
  • IV solution for injection

Administration instructions

  • One hour before meals for oral capsules
  • Specific preparation and administration instructions for oral suspension and IV solution

Instructions for patient response

  • Specific advice for patients on capsule administration and use of antacids

Additional precautions

  • Specific instructions for use in paediatric and geriatric patients
  • Considerations for hepatic and renal insufficiency

Toxicological information

  • Toxicity observed at high doses in animal studies
  • No specific antidote known for overdose

Storage guidelines

  • Specific instructions for storage conditions

Chemical information

  • Molecular formula and chemical structure details

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