Emparol 10 mg (Tablet)

Unit Price: ৳ 25.00 (1 x 14: ৳ 350.00)
Strip Price: ৳ 350.00

Medicine Details

Category Details
Generic Empagliflozin
Company Drug international ltd
Also available as

Title

  • Emparol 10 mg Tablet

Category

  • Medicine
  • Diabetes Care
  • Cardiovascular Health
  • Pharmacology
  • Therapeutic Class
  • Pregnancy & Lactation

Description

  • SGLT-2 inhibitor
  • Improves glycemic control
  • Reduces risk of cardiovascular death
  • Increases glucose excretion
  • Assists weight loss
  • Reduces blood pressure
  • Recommended dosage of 10 mg once daily
  • Can be taken with or without food
  • Potential side effects: urinary tract infections, female genital mycotic infections, dehydration, hypotension, weakness, dizziness, increased thirstiness
  • Storage conditions: cool & dry place below 30°C, protected from light & moisture
  • Chemical structure: Molecular formula C23H27ClO7
  • Common uses: control blood sugar, avoid long-term complications
  • May cause dehydration and increased urination
  • May cause hypoglycemia
  • May cause genital fungal and/or urinary tract infections
  • Requires regular blood sugar monitoring
  • Pregnancy warnings
  • Breast-feeding warnings
  • Affects kidney function
  • Affects liver function
  • Usable alone or in combination with other diabetes medicines

Dosage and administration

  • Recommended dose: 10 mg once daily
  • Increase to 25 mg once daily in patients tolerating Empagliflozin
  • Correct volume depletion before initiation

Interaction

  • Co-administration with diuretics results in increased urine volume
  • Co-administration with insulin or insulin secretagogues increases the risk for hypoglycemia
  • SGLT2 inhibitors increase urinary glucose excretion leading to positive urine glucose tests
  • Interference with 1,5-AG assay for glycemic control

Contraindications

  • Contraindicated in patients with serious hypersensitivity reaction to Empagliflozin or its ingredients
  • Contraindicated in severe renal impairment, end-stage renal disease, or dialysis

Side effects

  • Most common: urinary tract infections, female genital mycotic infections
  • Others: dehydration, hypotension, weakness, dizziness, increased thirstiness

Pregnancy and lactation

  • No adequate and controlled studies in pregnant women
  • Use during pregnancy if potential benefit justifies potential risk to the fetus
  • Not recommended when breastfeeding

Precautions and warnings

  • Assessment of renal function recommended before initiation and periodically thereafter
  • Not initiated in patients with eGFR less than 45 ml/min/1.73 m2
  • No dose adjustment needed in patients with eGFR greater than or equal to 45 ml/min/1.73 m2

Overdose effects

  • Supportive measures needed in case of overdose
  • Removal of Emparol by hemodialysis not studied

Chemical structure

  • Molecular formula: C23H27ClO7

Common questions

  • Commonly used to improve glycemic control in adults
  • Unsafe to use during pregnancy
  • Unsafe to use during breastfeeding
  • Caution required in patients with underlying kidney disease
  • No dose adjustment needed for patients with mild to moderate liver disease

Storage conditions

  • Keep in a cool & dry place below 30°C
  • Protected from light & moisture
  • Keep out of the reach of children

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