G-Prazosin SR 5 mg (Tablet (Extended Release))

Unit Price: ৳ 8.05 (10 x 10: ৳ 805.00)
Strip Price: ৳ 80.50

Medicine Details

Category Details
Generic Prazosin hydrochloride
Company Gonoshasthaya pharma ltd
Also available as
G prazosin 1 mg tablet G prazosin 2 mg tablet

Indications

  • Treatment of hypertension
  • Treatment of left ventricular failure
  • Treatment of Raynaud's phenomenon and disease
  • Symptomatic treatment of benign prostatic hyperplasia

Pharmacology

  • Decrease in total peripheral vascular resistance
  • Selective inhibition of alpha-1-adrenoreceptors
  • Reduction in left ventricular filling pressure
  • Reduction in cardiac impedance
  • Improvement of urinary pressure profile in men

Dosage & Administration

  • Low starting dose for best toleration
  • Dosage adjustment based on patient's response
  • Recommended starting dosage for different indications
  • Usual daily maintenance dosage for different indications
  • Use of Prazosin XR Extended-Release Tablets for hypertension
  • Dosage titration as clinically indicated
  • Addition of diuretic or other antihypertensive agent for hypotensive effect

Interaction

  • No adverse drug interaction observed in clinical experience
  • No interaction with cardiac glycosides, hypoglycemic agents, tranquilizers, antiarrhythmic agents, and analgesics

Contraindications

  • Known sensitivity to quinazolines

Side Effects

  • Dizziness
  • Headache
  • Drowsiness
  • Weakness
  • Palpitations
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Liver function abnormalities
  • Edema
  • Orthostatic hypotension
  • Dyspnea
  • Faintness
  • Tachycardia
  • Nervousness
  • Vertigo
  • Hallucinations
  • Depression
  • Rash
  • Pruritus
  • Alopecia
  • Urinary frequency
  • Impotence
  • Incontinence
  • Priapism
  • Blurred vision
  • Reddened sclera
  • Epistaxis
  • Tinnitus
  • Dry mouth
  • Nasal congestion
  • Diaphoresis
  • Fever
  • Positive ANA titer
  • Arthralgia

Pregnancy & Lactation

  • No teratogenic effects seen in animal testing
  • Caution advised during pregnancy and lactation

Precautions & Warnings

  • Risk of postural hypotension
  • Careful monitoring in patients with left ventricular failure, Raynaud's phenomenon/disease, and benign prostatic hyperplasia

Use in Special Populations

  • Not recommended for children under 12 years
  • Not recommended for left ventricular failure due to mechanical obstruction

Overdose Effects

  • Accidental ingestion effects in children
  • Support of cardiovascular system importance in case of hypotension
  • Monitoring and support of renal function
  • Not dialyzable because it is protein bound

Therapeutic Class

  • Alpha adrenoceptor blocking drugs

Storage Conditions

  • Keep away from light and moisture
  • Store below 30°C
  • Keep away from reach of children

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